39. Ma L, Li F, Zhang X, Chen H, Huang Q, Su J, Liu X, Sun T, Fang B, Liu K, Tang D,Wu D, Zhang W, Du L, Li S. Development of MEMS directed evolution strategy for multiplied throughput and convergent evolution of cytochrome P450 enzymes.Sci China Life Sci. 2021 Aug 31. Online ahead of print.
38. Qian M, Liu J, Zhao D, Cai P, Pan C, Jia W, Gao Y, Zhang Y, Zhang N, Zhang Y, Zhang Q,Wu D, Shan C, Zhang M, Schnabl B, Yang S, Shen X, Wang L. Aryl Hydrocarbon Receptor Deficiency in Intestinal Epithelial Cells Aggravates Alcohol-Related Liver Disease.Cell Mol Gastroenterol Hepatol. 2022, 13: 233-256.
37. Gao C, Xu Y, Liang Z, Wang Y, Shang Q, Zhang S, Wang C, Ni M,Wu D, Huang Z, Pang T. A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke. Acta Pharm Sin B. 2021, 11: 1867-1884.
36. Tie L*, Xiao H*, Wu D*, Yang Y, Wang P. A brief guide to good practices in pharmacological experiments: Western blotting. Acta Pharmacol Sin. 2021, 42: 1015-1017.（*共同通讯作者）
35. Zhong L, Diao X, Zhang N, Li F, Zhou H, Chen H, Bai X, Ren X, Zhang Y*, Wu D*, Bian X*. Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun. 2021, 12: 296.（*共同通讯作者）[入选“有机化学和化学生物学”领域焦点论文]
34. Dahlem C, Kado SY, He Y, Bein K, Wu D, Haarmann-Stemmann T, Kado NY, Vogel CFA. AHR signaling interacting with nutritional factors regulating the expression of markers in vascular inflammation and atherogenesis. Int J Mol Sci. 2020, 21: 8287.
33. Jiang K, Zhang Y, Chen Z, Wu D, Cai J, Gao X. Structural and functional insights into the C-terminal fragment of insecticidal Vip3A toxin of Bacillus thuringiensis. Toxins (Basel). 2020, 12: 438.
32. Xu M, Xu HH, Lin Y, Sun X, Wang LJ, Fang ZP, Su XH, Liang XJ, Hu Y, Liu ZM, Cheng Y, Wei Y, Li J, Li L, Liu HJ, Cheng Z, Tang N, Peng C, Li T, Liu T, Qiao L, Wu D, Ding YQ, Zhou WJ. LECT2, a ligand for Tie1, plays a crucial role in liver fibrogenesis. Cell. 2019, 178: 1478-1492. [获得F1000Prime推荐]
31. Wu D*, Su X, Lu J, Li S, Hood BL, Vasile S, Potluri N, Diao X, Kim Y, Khorasanizadeh S, Rastinejad F*. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019, 15: 367-376. （*共同通讯作者）[获得F1000Prime推荐]
30. Chandra V#, Wu D#, Li S, Potluri N, Kim Y, Rastinejad F. The quaternary architecture of RARβ-RXRα heterodimer facilitates domain-domain signal transmission. Nat Commun.2017, 8: 868.（#共同第一作者）
29. Wu D, Rastinejad F. Structural characterization of mammalian bHLH-PAS transcription factors. Curr Opin Struct Biol. 2017, 43: 1-9.
28. Smith SH, Jayawickreme C, Rickard DJ, Nicodeme E, Bui T, Simmons C, Coquery CM, Neil J, Pryor WM, Mayhew D, Rajpal DK, Creech K, Furst S, Lee J, Wu D, Rastinejad F, Willson TM, Viviani F, Morris DC, Moore JT, Cote-Sierra J. Tapinarof is a natural AhR agonist that resolves skin inflammation in mice and humans. J Invest Dermatol. 2017, 137: 2110-2119.
27. Wu D, Su X, Potluri N, Kim Y, Rastinejad F. NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. eLife. 2016, 5: e18790.
26. Vogel CF, Charrier JG,Wu D, McFall AS, Li W, Abid A, Kennedy IM, Anastasio C. Physicochemical properties of iron oxide nanoparticles that contribute to cellular ROS-dependent signaling and acellular production of hydroxyl radical. Free Radic Res. 2016, 50: 1153-1164.
25. Vogel CF, Chang WL, Kado S, McCulloh K, Vogel H, Wu D, Haarmann-Stemmann T, Yang G, Leung PS, Matsumura F, Gershwin ME. Transgenic overexpression of aryl hydrocarbon receptor repressor (AhRR) and AhR-mediated induction of CYP1A1, cytokines, and acute toxicity. Environ Health Perspect. 2016, 124: 1071-1083.
24. Wu D, Potluri N, Lu J, Kim Y, Rastinejad F. Structural integration in hypoxia-inducible factors. Nature. 2015, 524: 303-308. [在Nature同期News&Views栏目中被特别介绍，并获得F1000Prime推荐]
23. Vogel CF, Khan EM, Leung PS, Gershwin ME, Chang WL, Wu D, Haarmann-Stemmann T, Hoffmann A, Denison MS. Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-κB. J Biol Chem. 2014, 289: 1866-1875.
22. Wu D, Potluri N, Kim Y, Rastinejad F. Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain. Mol Cell Biol. 2013, 33: 4346-4356. [被编辑选为当期“意义显著”论文之一]
21. Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F. Multidomain integration in the structure of the HNF-4α nuclear receptor complex. Nature. 2013, 495: 394-398.
20. Vogel CF, Wu D, Goth SR, Baek J, Lollies A, Domhardt R, Grindel A, Pessah IN. Aryl hydrocarbon receptor signaling regulates NF-κB RelB activation during dendritic-cell differentiation. Immunol Cell Biol. 2013, 91: 568-575.
19. Vogel CF, Garcia J, Wu D, Mitchell DC, Zhang Y, Kado NY, Wong P, Trujillo DA, Lollies A, Bennet D, Schenker MB, Mitloehner FM. Activation of inflammatory responses in human U937 macrophages by particulate matter collected from dairy farms: an in vitro expression analysis of pro-inflammatory markers. Environ Health. 2012, 11: 17.
18. Wu D#, Nishimura N#, Kuo V, Fiehn O, Shahbaz S, Van Winkle L, Matsumura F, Vogel CF. Activation of aryl hydrocarbon receptor induces vascular inflammation and promotes atherosclerosis in apolipoprotein E-/- mice. Arterioscler Thromb Vasc Biol. 2011, 31: 1260-1267. （#共同第一作者）[被编辑在同期社论中推荐]
17. Wu D, Wong P, Li W, Vogel CF, Matsumura F. Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. Toxicology. 2011, 285: 97-103.
16. Wu D, Li W, Lok P, Matsumura F, Vogel CF. AhR deficiency impairs expression of LPS-induced inflammatory genes in mice. Biochem Biophys Res Commun. 2011, 410: 358-363.
15. Fujisawa Y, Li W, Wu D, Wong P, Vogel C, Dong B, Kung HJ, Matsumura F. Ligand-independent activation of the aryl hydrocarbon receptor by ETK (Bmx) tyrosine kinase helps MCF10AT1 breast cancer cells to survive in an apoptosis-inducing environment. Biol Chem. 2011, 392: 897-908.
14. Vogel CF, Li W, Wu D, Miller JK, Sweeney C, Lazennec G, Fujisawa Y, Matsumura F. Interaction of aryl hydrocarbon receptor and NF-κB subunit RelB in breast cancer is associated with interleukin-8 overexpression. Arch Biochem Biophys. 2011, 512: 78-86.
13. Dong B, Cheng W, Li W, Zheng J, Wu D, Matsumura F, Vogel CF. FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor. Biochim Biophys Acta. 2011, 1810: 427-431.
12. Sciullo EM, Vogel CF, Wu D, Murakami A, Ohigashi H, Matsumura F. Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages. Arch Toxicol. 2010, 84: 957-966.
11. Li W, Vogel CF, Wu D, Matsumura F. Non-genomic action of TCDD to induce inflammatory responses in HepG2 human hepatoma cells and in liver of C57BL/6J mice. Biol Chem.2010, 391: 1205-1219.
10. Han C, Hu T, Wu D, Qu S, Zhou J, Ding J, Shen X, Qu D, Jiang H. X-ray crystallographic and enzymatic analyses of shikimate dehydrogenase from Staphylococcus epidermidis. FEBS J. 2009, 276: 1125-1139.
9. Wu D, Kong Y, Han C, Chen J, Hu L, Jiang H, Shen X. D-Alanine-D-alanine ligase as a new target for the flavonoids quercetin and apigenin. Int J Antimicrob Agents. 2008, 32: 421-426.
8. Wu D, Zhang L, Kong Y, Du J, Chen S, Chen J, Ding J, Jiang H, Shen X. Enzymatic characterization and crystal structure analysis of the D-alanine-D-alanine ligase from Helicobacter pylori. Proteins. 2008, 72: 1148-1160.
7. Wu D, Hu T, Zhang L, Chen J, Du J, Ding J, Jiang H, Shen X. Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis. Protein Sci. 2008, 17: 1066-1076.
6. Hu T#, Wu D#, Chen J, Ding J, Jiang H, Shen X. The catalytic intermediate stabilized by a "down" active site loop for diaminopimelate decarboxylase from Helicobacter pylori. Enzymatic characterization with crystal structure analysis. J Biol Chem. 2008, 283: 21284-21293.（#共同第一作者）
5. Kong Y#, Wu D#, Bai H, Han C, Chen J, Chen L, Hu L, Jiang H, Shen X. Enzymatic characterization and inhibitor discovery of a new cystathionine γ-synthase from Helicobacter pylori. J Biochem. 2008, 143: 59-68.（#共同第一作者）
4. Zhang L#, Kong Y#, Wu D#, Zhang H, Wu J, Chen J, Ding J, Hu L, Jiang H, Shen X. Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay. Protein Sci. 2008, 17: 1971-1978.（#共同第一作者）
3. Kong D, Zhu W, Wu D, Shen X, Jiang H. Comparison of three 3D-QSAR methods using a novel class of MURF inhibitors. J Theor Comput Chem. 2007, 6: 63-80.
2. Cai J, Han C, Hu T, Zhang J, Wu D, Wang F, Liu Y, Ding J, Chen K, Yue J, Shen X, Jiang H. Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation. Protein Sci. 2006, 15: 2071-2081.
1. Luo H, Wu D, Shen C, Chen K, Shen X, Jiang H. Severe acute respiratory syndrome coronavirus membrane protein interacts with nucleocapsid protein mostly through their carboxyl termini by electrostatic attraction. Int J Biochem Cell Biol. 2006, 38: 589-599.
（下划线标注的为代表论文）
