代表性论文
1.Ma L, Li F, Zhang X, Chen H, Huang Q, Su J, Liu X, Sun T, Fang B, Liu K, Tang D, Wu D, Zhang W, Du L, Li S*. Development of MEMS directed evolution strategy for multiplied throughput and convergent evolution of cytochrome P450 enzymes. Sci China Life Sci,2022,65(3): 550-560. (IF: 6.038)
2.Guo J, Li F, Cheng F,Ma L, Liu X, Durairaj P, Zhang G, Tang D, Long X, Zhang W, Du L, Zhang X*, Li S. Bacterial biosynthetic P450 enzyme PikCD50N: a potential biocatalyst for the preparation of human drug metabolites. J Org Chem, 2021, 86(21): 14563-14571. (IF: 4.354)
3.You C, Li F, Zhang X,Ma L, Zhang YZ, Zhang W, Li S*. Structural basis for substrate specificity of the peroxisomal acyl-CoA hydrolase MpaH’involved in mycophenolic acid biosynthesis. FEBS J, 2021, 288, 5768-5780.(IF: 5.542)
4.Li F,Ma L, Zhang X, Chen J, Qi F, Huang Y, Qu Z, Yao L, Zhang W, Kim ES, Li S.Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 fromSebekia benihana.Synth Syst Biotechnol, 2020, 5(3): 236-243. (IF: 4.708)
5.Dong S, Chen J, Zhang X, Guo F,Ma L, You C, Wang X, Zhang W, Wan X, Liu SJ, Yao LS, Li S, Du L*, Feng Y*. Structural basis for selective oxidation of phosphorylated ethylphenolsby cytochrome P450 monooxygenase CreJ. Appl Environ Microbiol, 2021, 87: e00018-21. (IF: 4.792)
6.Li Z, Jiang Y, Zhang X, Chang Y, Li S, Zhang X, Zheng S, Geng C, Meng P,Ma L, Yang Y, Gao Z, Tang YJ, Li S*. Fragrant venezuelaenes A and B with a 5−5−6−7 tetracyclic skeleton: discovery, biosynthesis, and mechanisms of central catalysts.ACS catalysis, 2020, 10, 5846-5851. (IF: 13.084)
7.Li Z#, Jiang Y#, Guengerich FP,Ma L, Li S, Zhang W*. Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications.J Biol Chem. 2020, 295(3): 833-849. (IF: 5.517)
8.Xu H, Liang W, Ning L, Jiang Y, Yang W, Wang C, Qi F,Ma L, Du L, Fourage L, Zhou Y J, Li S*. Directed evolution of P450 fatty acid decarboxylases via high-throughput screening towards improved catalytic activity. ChemCatChem, 2019, 11, 1-6.(IF: 5.686)
9.Yao Q#,Ma L#, Liu L, Ikeda H, Fushinobu S, Li S, Xu LH*. Hydroxylation of Compactin (ML-236B) by CYP105D7 (SAV_7469) fromStreptomyces avermitilis. J Microbiol Biotechnol, 2017, 27(5): 956-964. (IF: 2.351)
10.Sun Y#,Ma L#, Han D#, Du L, Qi F, Zhang W, Sun J, Huang S, Kim ES*, Li S*.In vitroreconstitution of the cyclosporine specific P450 hydroxylases using heterologous redox partner proteins. J Ind Microbiol Biotechnol, 2017, 44(2):161-166.(IF: 3.346)
11.Du L,Ma L, Qi F, Zheng X, Jiang C, Li A, Wan X, Liu SJ*, Li S*. Characterization of a unique pathway for 4-cresol catabolism initiated by phosphorylation inCorynebacterium glutamicum. J Biol Chem, 2016, 291(12): 6583-6594.(IF:5.157)
12.Ma L, Du L, Chen H, Sun Y, Huang S, Zheng X, Kim ES, Li S*. Reconstitution of thein vitroactivity of the cyclosporine-specific P450 hydroxylase fromSebekia benihanaand development of a heterologous whole cell biotransformation system. Appl Environ Microbiol. 2015, 81(18), 6268-6275.(IF: 4.792)
13.Li C#,Ma L#, Mou S, Wang Y, Zheng Z, Liu F, Qi X, An M, Chen H, Miao J*. Cyclobutane Pyrimidine Dimers Photolyase from Extremophilic Microalga: Remarkable UVB Resistance and Efficient DNA Damage Repair, Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2015, 773: 37-42. (IF: 3.68)
14.Liu X#, Song F#,Ma L, Chen C, Xiao X, Ren B, Liu X, Dai H,Piggott AM, Av-Gay Y, Zhang L*, Capon RJ*. Sydowiols A–C:Mycobacterium tuberculosisprotein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus,Aspergillus sydowii. Tetrahedron Letters, 2013, 54(45):6081-6083. (IF: 2.415)
15.Ma L, Liu X, Liang H, Che Y, Chen C, Dai H, Yu K, Liu M, Ma LY, Yang CH, Song F, Wang Y*, Zhang L*. Molecular targets of 14-alpha-lipoyl andrographolide on quorum sensing inPseudomonas aeruginosa. Antimicrob Agents Chemother, 2012, 56(12): 6088-6094.(IF: 5.191)
16.Zeng X, Liu X, Bian J, Pei G, Dai H, Polyak SW, Song F,Ma L, Wang Y*, Zhang L*. Synergistic effect of AL-1 and various antibiotics on the formation of biofilms and production of exopolysaccharide and pyocyanin byPseudomonas aeruginosa.Antimicrobial Agents and Chemotherapy, 2011, 55(6): 3015-3017. (IF: 5.191)
17.Ma L, Chen J*, Liu R, Zhang XH, Jiang YA.Mutation ofrpoSgene decreased resistance to environmental stresses, synthesis of extracellular products and virulence ofVibrio anguillarum.FEMS Microbiol Ecol, 2009, 70(2): 130-136.(IF:4.194)