研究论文
*:通讯作者
★Zhu Y, Zeng Y, Liu M, Lu T, andPang X*. 2024.Rescue of morphological defects inStreptomyces venezuelaeby the alkaline volatile compound trimethylamine. Microbiology Spectrum 12(10):e0119524.
★Su W,Wang W, Li L, Zhang M, Xu H, Fu C,Pang X*, Wang M*. 2024. Mechanisms of tigecycline resistance in Gram-negative bacteria: A narrative review. Engineering Microbiology 4(3):100651.
★Zhu Y, Lu T, Zhang H, Liu M, andPang X*. 2024. SVEN_5003 is a major developmental regulator inStreptomyces venezuelae. Current Microbiology 81(6):166.
★ZhuY,WangX,ZhangJ,NiX, Zhang X, TaoM,andPangX*. 2022.wblAis the target of the orphan response regulatorOrrAinStreptomycescoelicolor.EnvironmentalMicrobiology 24(7):3081-3096.
★Zhu Y, Wang J, Su W, Ting Lu, Li A, andPang X*.2022.Effects of dual deletion ofglnRandmtrAon the expression ofnitrogen metabolismgenesinStreptomycesvenezuelae.MicrobialBiotechnology 15(6):1795-1810.
★ZhuY, Lu T, Ni X, Zhang X, Liu Y, Cui X,andPangX*. 2022. Mutation of MtrA at the predicted phosphorylation site abrogates its role as a global regulatorinStreptomycesvenezuelae.MicrobiologySpectrum 10(2):e0213121.
★Zhu Y,Zhang P,LuT,Wang X, Li A, Lu Y, Tao M,andPang X*.2021.Impact of MtrA on phosphate metabolism genes and the response to altered phosphate conditions inStreptomyces.EnvironmentalMicrobiology23(11):6907-6923.
★Liu M, Xu W, Zhu Y, Cui X, andPang X*.2021.The response regulator MacR and its potential in improvement of antibiotic production inStreptomyces coelicolor. Current Microbiology 78 (10):3696-3707.
★Zhu Y,LuT, Zhang J, Tao M, andPang X*. 2020.A novel XRE-family regulator that controls antibiotic production and development inStreptomyces coelicolor. Applied Microbiology and Biotechnology104(23):10075-10089.
★Zhu Y,Zhang P,Zhang J,Wang J,Lu Y,andPang X*. 2020.Impact on multiple antibiotic pathways reveals MtrA as a master regulator of antibiotic production inStreptomycesand potentially in other actinobacteria.Applied andEnvironmentalMicrobiology86(20): e01201-20.
★Zhu Y,Xu W, ZhangP,Zhao Z, Sheng D, Ma W, Zhang YZ, Bai L,andPang X*. 2020.A hierarchical network of four regulatory genes controls production of the polyene antibiotic Candicidin inStreptomycessp. FR-008.Applied andEnvironmentalMicrobiology86(9): e00055-20.
★Zhu Y, Zhang P, Zhang J, Xu W, Wang X, Wu L, Sheng D, Ma W, Cao G, Chen X, Lu Y, Zhang Y, andPang X*. 2019. The developmental regulator MtrA binds GlnR boxes and represses nitrogen metabolism genes inStreptomyces coelicolor.MolecularMicrobiology 112 (1):29-46.
★Liu M, Zhang P, Zhu Y, Lu T, Wang Y, Cao, G, Shi M, Chen X, Tao M, andPang X*.2019.Novel Two-Component system MacRS is a pleiotropic regulator that controls multiple morphogenic membrane protein genes inStreptomyces coelicolor.Applied andEnvironmentalMicrobiology 85 (4): e02178-18.
★Lu T, Zhu Y, Zhang P, Sheng D, Cao G,Pang X*. 2018. SCO5351 is a pleiotropic factor that impacts secondary metabolism and morphological development inStreptomyces coelicolor.FEMS Microbiology Letter365 (17), fny150.
★Zhang P, Wu L, Zhu Y, Liu M, Wang Y, Cao G, Chen XL, Tao M,Pang X*. 2017. Deletion of MtrA inhibits cellular development ofStreptomyces coelicolorand alters expression of developmental regulatory genes.Frontiers in Microbiology8:2013(1-18).
★Cao G, Zhang P, Gu Y,Pang X*. 2017.Gene Over expression inStreptomyces hygroscopicusAssociated with DNA amplification.Current Microbiology74:979-86.
★Zhao Z, Shi T, Xu M, Brock NL, Zhao YL, Wang Y, Deng Z,Pang X*, Tao M*. 2016. Hybrubins: Bipyrrole tetramic acids obtained by crosstalk between a truncated undecylprodigiosin pathway and heterologous tetramic acid biosynthetic genes.OrganicLETTERS18(3):572-5.
★Cao G, Howard ST, Zhang P, Wang X, Chen XL, Samten B, andPang X*. 2015.EspR, a regulator of the ESX-1 secretion system inMycobacterium tuberculosis,is directly regulated by the two-component systemsMprAB and PhoPR.Microbiology 161(3):477-489.
★Zhang P, Zhao Z, Li H, Chen XL, Deng Z, Bai L, andPang X*. 2015.Production of the antibiotic FR-008/Candicidin inStreptomycessp. FR-008 is coregulated by two regulators, FscRI and FscRIV, from different transcription factor families.Microbiology161(3):539-552.
★Zhang P, Wu H, Chen XL, Deng Z, Bai L, andPang X*. 2014. Regulation of the Biosynthesis of Thiopeptide Antibiotic Cyclothiazomycin by a Transcriptiona1 Regulator SHJG8833 inStreptomyces hygroscopicus5008.Microbiology 160 (7):1379-1392.
★Pang X*, Samten B, Cao G, Wang X, Tvinnereim A, Chen X, and Howard ST. 2013. MprAB regulates theespAoperon inMycobacterium tuberculosis, and modulates ESX-1 function and host cytokine response.Journal ofBacteriology 195(1):66-75.
★Pang X, Howard ST. 2007. Regulation of the alpha-crystallin gene acr2 by the MprAB two-component system ofMycobacterium tuberculosis.Journal ofBacteriology189(17):6213-21.
★Pang X, Vu P, Byrd TF, Ghanny S, Soteropoulos P, Mukamolova GV, Wu S, Samten B, Howard ST. 2007. Evidence for complex interactions of stress-associated regulons in an mprAB deletion mutant ofMycobacterium tuberculosis.Microbiology153(4):1229-42.
★Aigle B†,Pang X†, Decaris B, Leblond P. 2005. Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the dupliated type II polyketide synthase alp gene cluster inStreptomyces ambofaciens.Journal ofBacteriology187(7):2491-500.
★Pang X, Aigle B, Girardet JM, Mangenot S, Pernodet JL, Decaris B, Leblond P. 2004. Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of theStreptomyces ambofacienslinear chromosome.AntimicrobialAgents andChemotherapy48(2):575-88.
★Pang X, Zhou X, Sun Y, Deng Z. 2002.Physical map of the linear chromosome ofStreptomyces hygroscopicus10-22 deduced by analysis of overlapping large chromosomal deletions.Journal ofBacteriology184(7):1958-65.
