学术论文
1. Huilei Dong＃, Jinjing Li＃, Hongtan Liu, Shuaimin Lu, Junjie Wu, Youming Zhang, Yizhen Yin*, Yibing Zhao, Chuanliu Wu*. Design and Ribosomal Incorporation of Noncanonical Disulfide-Directing Motifs for the Development of Multicyclic Peptide Libraries.J. Am. Chem. Soc. 2022, 144, 5116–5125.
2. Daisuke Hazama＃,Yizhen Yin＃, Yoji Murata*, Makoto Matsuda, Takeshi Okamoto, Daisuke Tanaka, Naohiro Terasaka, Jinxuan Zhao, Mariko Sakamoto, Yuka Kakuchi, Yasuyuki Saito, Takenori Kotani, Yoshihiro Nishimura, Atsushi Nakagawa, Hiroaki Suga*, Takashi Matozaki*. Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy. Cell Chem. Biol. 2020, 27, 1181-1191. (Co-first author)
3.Yizhen Yin, Nobuaki Ochi, Timothy W. Craven, David Baker, Nagio Takigawa, Hiroaki Suga*. De novo carborane-containing macrocyclic peptides targeting human EGFR.J. Am. Chem. Soc. 2019, 141, 19193–19197.
4.Yizhen Yin＃, Qianran Fei＃, Weidong Liu, Zhuoru Li, Hiroaki Suga*, Chuanliu Wu*. Chemical and Ribosomal Synthesis of Topologically Controlled Bicyclic and Tricyclic Peptide Scaffolds Primed by Selenoether Formation.Angew. Chem. Int. Edit. 2019, 58, 4880-4885.
5. Alex Vinogradov,Yizhen Yin, Hiroaki Suga*. Macrocyclic peptides as drug candidates: recent progress and remaining challenges.J. Am. Chem. Soc. 2019, 141, 4167-4181.
6. Sayaka Imanishi, Takayuki Katoh,Yizhen Yin, Mituhiro Yamada, Marina Kawai,
Hiroaki Suga*. In Vitro Selection of Macrocyclic D/L-Hybrid Peptides against
Human EGFR.J. Am. Chem. Soc. 2021, 143, 5680–5684.
7. Emiko Mihara, Satoshi Watanabe, Nasir K. Bashiruddin, Nozomi Nakamura, Kyoko Matoba, Yumi Sano, Rumit Maini,Yizhen Yin, Katsuya Sakai, Takao Arimori, Kunio Matsumoto, Hiroaki Suga*, Junichi Takagi*. Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins.Nat. Commun. 2021, 12, 1543.
8.Yizhen Yin, Fener Chen*. Targeting human MutT homolog 1 (MTH1) for cancer
eradication: current progress and perspectives. Acta Pharm. Sin. B, 2020, 10, 2259–2271.
9. Changsheng Wu＃*,Yizhen Yin＃, Lele Zhu, Youming Zhang, Yue-Zhong Li*. Metagenomic sequencing-driven multidisciplinary approaches to shed light on the untapped microbial natural products.Drug Discov. Today 2022, 27, 730–742.
10. Yahong Tan＃, Junjie Wu＃, Lulu Song, Mengmeng Zhang, Christopher John Hipolito, Changsheng Wu, Siyuan Wang*, Youming Zhang,Yizhen Yin*. Merging the Versatile Functionalities of Boronic Acid with Peptides.Int. J. Mol. Sci. 2021, 22, 12958.
11. Jia-Qi Hu, Jing-Jing Wang, Yue-Lan Li, Li Zhuo, Ai Zhang, Hai-Yan Sui, Xiao-Ju Li, Tao Shen,Yizhen Yin, Zhi-Hong Wu, Wei Hu, Yue-Zhong Li*, Changsheng Wu*. Combining NMR-Based Metabolic Profiling and Genome Mining for the Accelerated Discovery of Archangiumide, an Allenic Macrolide from the Myxobacterium Archangium violaceum SDU8.Org. Lett. 2021, 23, 2114–2119.
12.Yizhen Yin, Shigeki Sasaki, Yosuke Taniguchi*. Effects of 8-halo-7-deaza-2'-deoxyguanosine triphosphate on DNA synthesis by DNA polymerases and cell proliferation.Bioorg. Med. Chem. 2016, 24, 3856-3861.
13.Yizhen Yin, Shigeki Sasaki, Yosuke Taniguchi*. Inhibitory Effect of 8-Halogenated-7-deaza-2'-deoxyguanosine Triphosphates on Human 8-Oxo-2'-deoxyguanosine Triphosphatase, hMTH1, Activities.ChemBioChem 2016, 17, 566-569.
14.Yizhen Yin, Shigeki Sasaki, Yosuke Taniguchi*. Recognition and excision properties of 8-halogenated-7-deaza-2'-deoxyguanosine as 8-oxo-2'-deoxyguanosine analogues and Fpg and hOGG1 inhibitors. ChemBioChem 2015, 16, 1190-1198.
15.Yizhen Yin, Yosuke Taniguchi*, Shigeki Sasaki*. Synthesis of 8-Halogenated-7-deaza-2'-deoxyguanosine as an 8-Oxo-2'-deoxyguanosine Analogue and Evaluation of its Base Pairing Properties.Tetrahedron 2014, 70, 2040-2047.
16.Yizhen Yin, Chao Liu, Long-Qian Tang and Zhao-Peng Liu*. Recoverable Pd/C
catalyst mediated dehydrogenation of sterols and an improved synthesis of 1α-hydroxydehydroepiandrosterone.Steroids 2012, 77, 1419–1422.
17.Yizhen Yin, Jian-Ping Li, Chao Liu, Long-Qian Tang and Zhao-Peng Liu*. Advances in the Synthesis of A-Ring 1,7-Enyne Synthons for Active Vitamin D3 Analogues.Curr. Org. Synth. 2011, 8, 374-392.
18. Bing-Lei Gao, Cheng-Mei Zhang,Yi-Zhen Yin, Long-Qian Tang, Zhao-Peng Liu*. Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands.Bioorg. Med. Chem. Lett. 2011, 21, 3730-3733.
