代表性论文
1. Liu, Y.#andWang, H.*（独立通讯作者）, Reply to: Docking domains from modular polyketide synthases and their use in engineering.Nature Communications, 2025. 16(1).（IF=17.2，综合性一区Top期刊）
2. Jiang, C.#; Hao, K.; Wang, S.; Guo, R.; Li, X.; Lv, L.; Luan, J.;Wang, H.*（独立通讯作者）, Developing the protein quality control system inStreptomycesfor selective translation of ultra-long full-length polyketide synthase mRNAs to enhance biosynthesis efficiency.Synthetic and Systems Biotechnology.已接收（IF=4.5，生物工程与应用微生物一区Top期刊）
3. Cui, T.#; Jiang, C.; Li, J.; Wang, S.; Li, L.; Luan, J.;Wang, H.*（独立通讯作者）, Modular engineering of the doxorubicin biosynthetic gene cluster based on component functional clustering inStreptomyces.Journal of Biotechnology, 2025. 408: p. 265-274.（IF=3.8，生物学二区）
4. Guan, Z.#;Wang, H.*（并列通讯作者）and Feng, Q.*, Establishment and improvement of genetic manipulation tools forFusobacterium nucleatum.Engineering Microbiology, 2025. 5(1): p. 100192.
5. Zhang, H.#; Zhu, R.; Wang, Z.; He, R.; Zhang, Y.; Luan, J.; Yan, Y.; Zhang, Y.;Wang, H.*（独立通讯作者）, Programming virulent bacteriophages by developing a multiplex genome engineering method.mBio, 2025, p. e0358224.（IF=5.5，微生物学二区Top期刊）
6. Liu, Y.#; Song, C.; Cui, Q.; Sun, H.; Jiang, C.; Guo, R.; He, R.; Li, Z.; Luan, J.; &Wang, H.*（独立通讯作者）, Improving polyketide biosynthesis by rescuing the translation of truncated mRNAs into functional polyketide synthase subunits,Nature Communications,2025, 16(1).（IF=17.2，综合性一区Top期刊）
7. Yang, Y.#; Yuan, H.; Zhang, Y.; Luan, J.; &Wang, H.*（独立通讯作者）, Progress in African swine fever vector vaccine development,International Journal of Molecular Sciences, 2025, 26(3):921（IF=5.7，生化与分子生物学三区）
8.Luan, J.#; Song, C.; Liu, Y.; He, R.; Guo, R.; Cui, Q.; Jiang, C.; Li, X.; Hao, K.; Stewart, A. F.; Fu, J.; Zhang, Y. &Wang, H.*（独立通讯作者）,Seamless site-directed mutagenesis in complex cloned DNA sequences using the RedEx method,Nature Protocols,2024,19(11), 3360-3388.（IF=19.4，生化研究方法一区Top期刊）
9.Yu, G.#; Duan, Q.; Cui, T.; Jiang, C.; Li, X.; Li, Y.; Fu, J.; Zhang, Y.;Wang, H.*（并列通讯作者）& Luan, J.*, Development of a bacterial gene transcription activating strategy based on transcriptional activator positive feedback,Journal of Advanced Research, 2023,66, 155-164.（IF=11.6，综合性一区Top期刊）
10.Li, X.#; Guo, R.; Luan, J.; Fu, J.; Zhang, Y. &Wang, H.*（独立通讯作者）, Improving spinosad production by tuning expressions of the forosamine methyltransferase and the forosaminyl transferase to reduce undesired less active byproducts in the heterologous hostStreptomyces albusJ1074,MicrobialCell Factories, 2023, 22(1), 15.（IF=6.1，生物工程与应用微生物二区）
11.Jiang, C.#; She, Q. &Wang, H.*（独立通讯作者）, Editorial: Insights in genome editing tools and mechanisms: 2022.Frontiers in Genome Editing, 2023, 5, 1240576.（IF=4.9，生物工程与应用微生物二区）
12.李雨桐#，崔天琦，张海林，于广乐，栾霁*，王海龙*（主通讯作者），肿瘤靶向细菌Escherichia coliNissle 1917在癌症治疗中的研究进展，中国生物工程杂志，2023, 43(6): 54-68.
13.姜婵娟#，崔天琦，孙洪娈，焦念志，符军，张友明*，王海龙*（主通讯作者），ExoCET-BAC策略高效抓取和组装高AT含量基因组大片段，合成生物学，2022,3(1):238-251.获得“《合成生物学》期刊2024年度优秀论文”
14.Jiang, T.#,*; Yang, X.#; Li, G.; Zhao, X.; Sun, T.; Muller, R.;Wang, H. *（并列通讯作者）; Li, M.* & Zhang, Y.*, Bacteria-Based Live Vehicle for In Vivo Bioluminescence Imaging,AnalyticalChemistry, 2021, 93(47), 15687-15695.（IF=6.6,化学一区Top期刊）
15.Tang, Y.#; Zhang, C.; Cui, T.; Lei, P.; Guo, Z. *;Wang, H. *（并列通讯作者）& Liu, Q. *, The Discovery of Actinospene, a New Polyene Macrolide with Broad Activity against Plant Fungal Pathogens and Pathogenic Yeasts,Molecules, 2021, 26(22).（IF=5.0,生化与分子生物学三区）
16.Song, C.#; Luan, J.#; Li, R.; Jiang, C.; Hou, Y.; Cui, Q.; Cui, T.; Tan, L.; Ma, Z.; Tang, Y. J.; Stewart, A. F.; Fu, J.; Zhang, Y. &Wang, H.*（独立通讯作者）, RedEx: a method for seamless DNA insertion and deletion in large multimodular polyketide synthase gene clusters,Nucleic Acids Research, 2020, 48(22), e130.（IF=16.8,生化与分子生物学二区Top期刊）
17.Jiang, C.#; Zhou, H.; Sun, H.; He, R.; Song, C.; Cui, T.; Luan, J.; Fu, J.; Zhang, Y.; Jiao, N.;Wang, H.*（独立通讯作者）,Establishing an efficient salinomycin biosynthetic pathway in three heterologousStreptomyceshosts by constructing a 106-kb multioperon artificial gene cluster,Biotechnology & Bioengineering,2021, 118: 4668-4677. (IF=3.8，生物工程与应用微生物三区)
18.Abbasi, M. N.#; Fu, J.; Bian, X.;Wang, H.*（并列通讯作者）; Zhang, Y.* & Li, A.*, Recombineering for Genetic Engineering of Natural Product Biosynthetic Pathways,Trends in Biotechnology, 2020, 38(7), 715-728.（IF=16.6，生物工程与应用微生物一区Top期刊）
19.Song, C.#; Luan, J.#; Cui, Q.; Duan, Q.; Li, Z.; Gao, Y.; Li, R.; Li, A.; Shen, Y.; Li, Y.; Stewart, A. F.; Zhang, Y.*; Fu, J.* &Wang, H.*（主通讯作者）, Enhanced heterologous spinosad production from a 79-kb synthetic multi-operon assembly,ACS Synthetic Biology, 2019, 8(1), 137-147.（IF=4.3，生化研究方法一区）
20.Wang, H.#（第一作者）; Li, Z.; Jia, R.; Yin, J.; Li, A.; Xia, L.; Yin, Y.; Muller, R.; Fu, J.*; Stewart, A. F.* & Zhang, Y.*, ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes,Nucleic Acids Research, 2018, 46(5), e28.（IF=16.8,生化与分子生物学二区Top期刊）
21.Wang, H.#（并列第一作者）; Li, Z.#; Jia, R.; Hou, Y.; Yin, J.; Bian, X.; Li, A.; Muller, R.; Stewart, A. F.*; Fu, J.* & Zhang, Y.*, RecET direct cloning and Redab recombineering of biosynthetic gene clusters, large operons or single genes for heterologous expression,Nature Protocols, 2016, 11(7), 1175-1190.（IF=19.4，生化研究方法一区Top期刊）
22.Wang, H.#（第一作者）; Bian, X.; Xia, L.; Ding, X.; Müller, R.; Zhang, Y.*; Fu, J.* & Stewart, A. F.*, Improved seamless mutagenesis by recombineering usingccdBfor counterselection,Nucleic Acids Research, 2014, 42(5), e37.（IF=16.8,生化与分子生物学二区Top期刊）
23.Jing, X.#; Cui, Q.#; Li, X.; Yin, J.; Ravichandran, V.; Pan, D.; Fu, J.; Tu, Q.;Wang, H.*（并列通讯作者）; Bian, X.* & Zhang, Y.*, EngineeringPseudomonas protegensPf-5 to improve its antifungal activity and nitrogen fixation,Microbial Biotechnology, 2020, 13(1), 118-133.（IF=5.9，生物工程与应用微生物二区）
24.Luan, J.#; Li, Z.#;Wang, H.*（独立通讯作者）; Fu, J. & Zhang, Y.,In vitroassay revealed mismatches between guide RNA and target DNA can enhance Cas9 nuclease activity,Current Chinese Science, 2020, 1(1), 69-72.
25.Zhang, Y.#; Liu, R.#; Tian, K.#; Wang, Z.#; Yang, X.; Gao, D.; Zhang, Y.; Fu, J.*;Wang, H.*（并列通讯作者）& Zhao, J.*, Fiber2 and hexon genes are closely associated with the virulence of the emerging and highly pathogenic fowl adenovirus 4,Emerging Microbes & Infections, 2018, 7(1), 199.（IF=7.2，微生物学一区Top期刊）
26.Wang, H.#（第一作者）; Yao, T.; Cai, M.; Xiao, X.; Ding, X. & Xia, L.*, A genome walking strategy for the identification of nucleotide sequences adjacent to known regions,Biotechnology Letters, 2013, 35(2), 279-284.
27.Sun J.; Yu, X.; Tang G.;Chen. M.; Zheng Y.; Hu Y.; Li, Q.; Li, X.; Li, N.; Li, Z.; Li, Y.; Lu, N.; Tan, W.; Yang Y.; Lyu X.; Zhao, G.;Wang, H.; Dai, L.; Zhao, G.; Ai, L.*; Zhao, W.*, A CRISPR-SpCas9M-reporting system for efficient and rapid genome editing in Caulobacter crescentus.Nucleic Acids Research, 2025. 53(8).
28.Yu, G.#; Li, X.; Duan, Q.; Fu, J.; Zhang, Y.;Wang, H.& Luan J.*, Systematic identification of endogenous strong constitutive promoters from the diazotrophic rhizosphere bacteriumPseudomonas stutzeriDSM4166 to improve its nitrogenase activity.Microbial Cell Factories, 2023, 22(1): 91.
29.Hao, Y.#; Fu, J.; Zhang, J.; Du,N.; Ta, H.; Zhu, T.;Wang, H.; Lou, H.; Cheng, A.*, Identification and Functional Characterization of UDP-Glycosyltransferases Involved in Isoflavone Biosynthesis in Astragalus membranaceus.Journal of Agricultural and Food Chemistry, 2023. 71(34): p. 12775-12784.
30.Rostovskaya, M.#, Fu, J., Obst, M., Baer, I., Weidlich, S.,Wang, H., Smith, A. J. H., Anastassiadis, K.* & Stewart, A. F.*, Transposon-mediated BAC transgenesis in human ES cells,Nucleic Acids Research, 2012, 40(19), e150.
31.Zhang, W.#, Fu, J.#, Liu, J.,Wang, H., Schiwon, M., Janz, S., Schaffarczyk, L., von der Goltz, L., Ehrke-Schulz, E., Domer, J., Solanki, M., Boehme, P., Bergmann, T., Lieber, A., Lauber, C., Dahl, A., Petzold, A., Zhang, Y.*, Stewart, A. F.* & Ehrhardt, A.*, An engineered virus library as a resource for the spectrum-wide exploration of virus and vector diversity,Cell Reports, 2017, 19(8), 1698-1709.
32.Zhang, W.#, Fu, J., Liu, J.,Wang, H., Schulz, E., Solanki, M., Boehme, P., Gebbing, M., Bergmann, T., Doerner, J., Stewart, A. F. & Ehrhardt, A.*, High-throughput cloning and tagging of an engineered adenovirus-library empowers vector diversity for broad applications,Molecular Therapy, 2015, 23, S21.
33.Bian, X.#, Tang, B.#, Yu, Y., Tu, Q., Gross, F.,Wang, H., Li, A., Fu, J., Shen, Y., Li, Y., Stewart, A. F., Zhao, G., Ding, X.*, Muller, R.* & Zhang, Y.*, Heterologous production and yield improvement of epothilones inBurkholderialesstrain DSM 7029,ACS Chemical Biology, 2017, 12(7), 1805-1812.
34.Yin, J.#,Wang, H., Li, R., Ravichandran, V., Bian, X., Li, A., Tu, Q., Stewart, A.F., Fu, J.* & Zhang, Y.*, A practical guide to recombineering inPhotorhabdusandXenorhabdus,Current Topics in Microbiology and Immunology, 2017.
35.Ravichandran, V.#, Zhong, L.,Wang, H., Yu, G., Zhang, Y.*& Li, A.*, Virtual screening and biomolecular interactions of CviR-based quorum sensing inhibitors against chromobacterium violaceum,Frontiers in Cellular and Infection Microbiology, 2018, 8, 292.
36.Liu, Q.#, Shen, Q.#, Bian, X., Chen, H., Fu, J.,Wang, H., Lei, P., Guo, Z., Chen, W.*, Li, D.* & Zhang, Y.*, Simple and rapid direct cloning and heterologous expression of natural product biosynthetic gene cluster inBacillus subtilisvia Red/ET recombineering,Scientific Reports, 2016, 6, 34623.
37.Jiang, B.#, Zhang, R., Feng, D., Wang, F., Liu, K., Jiang, Y., Niu, K., Yuan, Q., Wang, M.,Wang, H., Zhang, Y. & Fang, X.*, A Tet-on and Cre-loxP based genetic engineering system for convenient recycling of selection markers inPenicillium oxalicum,Frontiers in Microbiology, 2016, 7, 485.
38.Zhu, L.#, Yue, X., Han, K., Li, Z., Zheng, L., Yi, X.,Wang, H., Zhang, Y. & Li, Y.*, Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes inMyxococcus xanthus,Microbial Cell Factories, 2015, 14, 105.
39.Bian, X.#, Huang, F.,Wang, H., Klefisch, T., Muller, R.* & Zhang, Y.*, Heterologous production of glidobactins/luminmycins inEscherichia coliNissle containing the glidobactin biosynthetic gene cluster fromBurkholderiaDSM7029,Chembiochem, 2014, 15(15), 2221-2224.
40.Yu, F.#, Jing, X., Li, X.,Wang, H., Chen, H., Zhong, L., Yin, J., Pan, D., Yin, Y., Fu, J., Xia, L., Bian, X., Tu, Q. & Zhang, Y., Recombineering Pseudomonas protegens CHA0: An innovative approach that improves nitrogen fixation with impressive bactericidal potency,Microbiology Research, 2019, 218, 58-65.
41.Fu, J.#; Bian, X.#; Hu, S.;Wang, H.; Huang, F.; Seibert, P. M.; Plaza, A.; Xia, L.; Müller, R.*; Stewart, A. F.* & Zhang, Y.*, Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting,Nature Biotechnology, 2012, 30(5), 440-446.
