发表论文(#第一作者;*通讯作者)
1.Wang, C. Y.; Hu, J. Q; Wang, D. G.; Li, Y.-Z.*;Wu, C.*Recent advances in discovery and biosynthesis of natural products from myxobacteria: an overview from 2017 to 2023.Nat. Prod. Rep.2024,https://doi.org/10.1039/D3NP00062A
2.Zhu, L. L.#; Yang, Q. Y.#; Wang, D. G.#; Niu, L.; Pan, Z.; Li, S. Li, Y.-Z.*; Zhang, W*; andWu, C.*. Deciphering The Biosynthesis and Physiological Function of 5-Methylated Pyrazinones Produced by Myxobacteria.ACS Cent. Sci.2024,10.1021/acscentsci.3c01363
3.Wang, D. G.; Wang, C. Y.; Hu, J. Q; Wang, J. J.; Liu, W. C.; Zhang, W. J.; Du, X. R.; Wang, H.; Zhu, L. L.; Sui, H. Y.; Li, Y.-Z.*;Wu, C.*Constructing a Myxobacterial Natural Products Database to Facilitate NMR-based Metabolomics Bioprospecting of Myxobacteria.Anal. Chem.2023,95,5256−5266 .
4.Hu, J. Q; Zhang, A.; Wang, H.; Luo, N.; Wang, Q. X.; Zhu, L. L.; Li, Y. Z.;Wu, C.*Discovery and Biosynthesis of Glycosylated Cycloheximide from a Millipede-Associated Actinomycete.J. Nat. Prod.2023, 86, 340-345.
5.Zhang, L.; Wang, D. G.; Zhang, P.;Wu, C.*; Li, Y. Z.*Promiscuity Characteristics of Versatile Plant Glycosyltransferases for Natural Products Glycodiversification.ACS Synth. Biol.2022, 11, 812−819.
6.Zhang, P.; Zhang, L.;Diao, X. T.; Li, S.; Li, D. D.; Zhang, Z.; Fang, J.; Tang, Y. J.; Wu, D. L.;Wu, C.*; Li, Y. Z.*Docking-guided rational engineering of a macrolide glycosyltransferase to glycodiversify epothilone B.Commun. Biol.2022,5:100
7.Wu, C.*,#;Yin, Y.#; Zhu, L. L.; Zhang, Y. M.; Li, Y. Z.* Metagenomic Sequencing Driven Multidisciplinary Approaches to Shed Light on The Untapped Microbial Natural Products.Drug Discovery Today.2022, 27, 730−742.
8.Hu, W. F.#; Niu, L.#; Yue, X. J.; Zhu, L. L.; Hu, W.; Li, Y.-Z.*;Wu, C.*Characterization of Constitutive Promoters for The Elicitation of Secondary Metabolites in Myxobacteria.ACS Synth. Biol.2021, 10, 2904−2909.
9.Wang, D. G.#; Niu, L.#; Lin, Z. M.; Wang, J. J.; Gao, D. F.; Sui, H. Y.; Li, Y. Z. *;Wu, C.*The Discovery and Biosynthesis of Nicotinic Myxochelins from anArchangiumsp. SDU34.J. Nat. Prod.2021,84, 2744−2748.
10.Li, Y.#; Zhuo L.#; Li, X.; Zhu, Y.; Wu, S.; Shen, T.; Hu, W.; Li, Y.-Z.*;Wu, C.*Myxadazoles, Myxobacterium-Derived Isoxazole-Benzimidazole Hybrids with Cardiovascular Activities.Angew. Chem. Int. Ed.2021,60, 21679 –21684.
11.Hu, J. Q#; Wang, J. J.#; Li, Y. L.; Zhuo, L.; Zhang, A.; Sui, H. Y.; Li, X. J.; Shen, T.; Wu, Z. H.; Hu, W.; Li, Y. Z.*;Wu, C.*Combining NMR-based metabolic profiling and genome mining for the accelerated discovery of archangiumide, an allenic macrolide from the myxobacteriumArchangium violaceumSDU8.Org. Lett.2021,23, 2114–2119.
12.Zhang, P.; Zhang, Z.; Zhang, L. J.; Wang, J. J.;Wu, C.*Glycosyltransferase GT1 family: Phylogenetic distribution, substrates coverage, and representative structural features.Comput. Struct. Biotechnol. J.2020,18, 1383–1390.
13.Zhang, P.; Zhang, L.; Yue, X. J.; Tang, Y. J.;Wu, C.*;Li, Y. Z.*Effects of glycosylation on the bioactivity of rapamycin.Appl. Microbiol. Biotechnol.2020, 104, 9125-9134.
14.Zhang, P.; Zhang, Z.; Li, Z. F.; Chen, Q.; Li, Y. Y.; Gong, Y.; Yue, X. J.; Sheng, D. H.; Zhang, Y. M.;Wu, C.*;Li, Y. Z.*Phylogeny-guided Characterization of Glycosyltransferases for Epothilone Glycosylation.Microbiol. Biotech.2019, 12, 763-774.
15.Wu, C.#; Shang Z.#; Lemetre C.; Ternei M. A. ; Brady S. F.; Cadasides, calcium-dependent acidic lipopeptides from the soil metagenome that are active against multidrug resistant bacteria.J. Am. Chem. Soc.2019, 141, 3910-3919.
16.Machushynets N.;Wu, C. *;Elsayed S. S.; Hankemeier T.; van Wezel G. P. * Discovery of novel glycerolated quinazolinones fromStreptomycessp. MBT27.J. Ind. Microbiol. Biotechnol.2019. 46, 483-492.
17.Wu, C.;van der Heul, H. U.; Melnik, A. V.; Luebben, J.; Pannu, N.; Dorrestein, P. C.; Choi, Y. H.; van Wezel, G. P. Lugdunomycin, an angucycline-derived molecule with unprecedented chemical architecture.Angew. Chem. Int. Ed.2019,58, 2809 –2814.
18.Gubbens, J.;Wu, C.; Zhu, H.; Filippov, D. V.; Florea, B. L.; Rigali, S.; Overkleeft, H. S.; van Wezel, G. P. Intertwined Precursor Supply during Biosynthesis of the Catecholate–Hydroxamate Siderophores Qinichelins inStreptomycessp. MBT76.ACS Chem. Biol.2017, 12, 2756–2766.
19.Wu, C.;Du, C.;Ichinose, K.; Choi, Y. H.; van Wezel, G. P. Discovery ofC-glycosylpyranonaphthoquinones inStreptomycessp. MBT76 by a combined NMR-based metabolomics and bioinformatics workflow.J. Nat. Prod.2017,80, 269–277.
20.Wu, C.; Ichinose, K.; Choi, Y. H.; van Wezel, G. P. Aromatic Polyketide GTRI-02 is a previously unidentified product of the act gene cluster inStreptomyces coelicolorA3(2).ChemBioChem.2017,18, 1428–1434.
21.Wu, C.;Medema, M. H.; Läkamp, R. M.; Zhang, L.; Dorrestein, P. C.; Choi, Y. H.; van Wezel, G. P. Leucanicidin and Endophenasides Result from Methyl-Rhamnosylation by the Same Tailoring Enzymes inKitasatosporasp. MBT66.ACS Chem. Biol.2016,11, 478–490.
22.Wu, C.#;Zhu, H.#; van Wezel, G. P.; Choi, Y. H. Metabolomics-guided analysis of isocoumarin production by Streptomyces species MBT76 and biotransformation of flavonoids and phenylpropanoids.Metabolomics2016, 12:90.
23.Wu, C.; Choi, Y. H.; van Wezel, G. P. Metabolic profiling as a tool for prioritizing antimicrobial compounds.J. Ind. Microbiol. Biotechnol.2016,43, 299–312.
24.Wu, C.; Du, C.; Gubbens, J.; Choi, Y. H.; van Wezel, G. P. Metabolomics-Driven Discovery of a Prenylated Isatin Antibiotic Produced byStreptomycesSpecies MBT28.J. Nat. Prod.2015,78, 2355–2363.
25.Wu, C.; Kim, H. K.; van Wezel, G. P.; Choi, Y. H. Metabolomics in the natural products field – a gateway to novel antibiotics.Drug Discov. Today Technol.2015,13, 11–17.
26.Wu, C.; Zacchetti, B.; Ram, A. F. J.; van Wezel, G. P.; Claessen, D.; Choi, Y. H. Expanding the chemical space for natural products byAspergillus-Streptomycesco-cultivation and biotransformation.Sci. Rep.2015,5, 10868.
27.Wu, C.; van Wezel, G. P.; Choi, Y. H. Identification of novel endophenaside antibiotics produced byKitasatosporasp. MBT66.J. Antibiot.2015,68, 445–452.
28.Wu, C.; Lin, Z.; Wang, L.; Guo, D. Phenolic Compounds with NF-κB Inhibitory Effects from the FungusPhellinus baumii.Bioorg. Med. Chem. Lett.2011,21, 3261–3267.