教育背景:
博士 2010.10-2014.12 荷兰格罗宁根大学 专业:微生物生理
硕士 2007.09-2010.07 山东大学 专业:微生物
学士 2003.09-2007.07 山东大学 专业:生命科学基地
工作经历:
2023.09-现在 山东大学微生物技术研究院 教授
2016.12-2023.09 山东大学微生物技术研究院 副研究员
2015.01-2016.12 荷兰格罗宁根大学 博士后
研究方向:
丝状真菌蛋白分泌机制研究
丝状真菌天然产物研究
碳水化合物作用酶的挖掘及应用
代表性论文:
1. Li Z, Waghmare P, Dijkhuizen L,Meng X*, Liu W (2024) Research advances on the consolidated bioprocessing of lignocellulosic biomass. Engineering Microbiology, 4:100139
2. Fang Y, Dong M, van Leeuwen S, Dijkhuizen L,Meng X*, Liu W(2023) Biochemical characterization of glycoside hydrolase family 31 a-glucosidases fromMyceliophthora thermophilafor a-glucooligosaccharide synthesis. Int J Biol Macromol, 252:126452
3. Wang Z, Yang R, Lv W, Zhang W,Meng X*, Liu W (2022) Functional characterization of sugar transporter CRT1 reveals differential roles of its C-terminal region in sugar transport and cellulase induction inTrichoderma reesei. Microbiol Spectr, 10(4):e0087222.
4. Rawat PS, Li Y, Zhang W,Meng X*, Liu W (2022)Hungatella hathewayi, an efficient glycosaminoglycan-degrading firmicutes from human gut and its chondroitin ABC exolyase with high activity and broad substrate specificity. Appl Environ Microbiol, 88(22):e0154622.
5. Meng X, Li X, Pijning T, Wang X, van Leeuwen SS, Dijkhuizen L, Chen G*, Liu W* (2022) Characterization of the (engineered) branching sucrase GtfZ-CD2 fromApilactobacillus kunkeeifor efficient glucosylation of benzenediol compounds. Appl Environ Microbiol, 88(16):e0103122.
6. Meng X, Fang Y, Ding M, Zhang Y, Jia K, Li Z, Collemare J*, Liu W* (2021) Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity. Biotechnol Adv, 54:107866.
7. Liu L, Xu M, Cao Y, Wang H, Shao J, Xu M, Zhang Y, Wang Y, Zhang W,Meng X*, Liu W (2020) Biochemical characterization of xylanases fromStreptomyces sp.B6 and their application in the xylooligosaccharide production from viscose fiber production waste. J Agric Food Chem, 68(10):3184-3194.
8. Meng, X., Liu, H., Xu, W., Zhang, W., Wang, Z., & Liu, W*. (2020). Metabolic engineeringSaccharomyces cerevisiaefor de novo production of the sesquiterpenoid (+)-nootkatone. Microb Cell Fact, 19(1), 21.
9. Wang L, Zheng F, Zhang W, Zhong Y, Chen G,Meng X*,Liu W (2018) A copper-controlled RNA interference system for reversible silencing of target genes inTrichoderma reesei. Biotechnol Biofuels, 11: 33.
10. Meng X, Gangoiti J, de Kok N, van Leeuwen SS, Pijning T, Dijkhuizen L (2018) Biochemical characterization of two GH70 family 4,6-α-glucanotransferases with distinct product specificity fromLactobacillus aviariussubsp.aviariusDSM 20655. Food Chem, 253:236-246.
授权专利:
1. 一株高产岩藻糖基乳糖的酿酒酵母工程菌株及其应用,专利号:ZL202010187309.1,第一位
2. 一株优化的高产岩藻糖基乳糖的酿酒酵母菌株及其应用,专利号:ZL202010187362.9,第二位
3. 一种耐碱耐热的木聚糖酶及其应用,专利号:ZL201911194651.8,第二位