医药微生物技术

姜天宇

助理研究员
硕士生导师
个人简介 科研项目 学术论文

教育背景:

2012-09至2018-06,山东大学,药物化学,医学博士学位

2017-04至2018-05,美国得州农机(工)大学健康科学中心,生物科学与技术研究所,国家公派联合培养博士

2008-09至2012-06,山东大学,药学,理学学士学位

工作经历:

2022-02至今,山东大学,微生物技术国家重点实验室(研究院),助理研究员

2018-07至2022-02,山东大学,微生物技术国家重点实验室(研究院),博士后

研究方向:

1.肿瘤靶向活菌药物

2.微生物可视化分析

主要项目:

1.山东大学青年学者未来计划,2023.01-2027.12,50万元,主持;

2.国家自然科学基金青年科学基金项目,2023.01-2025.12,30万元,主持;

3.山东省自然科学基金青年项目,2021.01-2023.12,15万元,主持;

4.广东省基础与应用基础研究基金—区域联合基金青年项目,2020.10-2023.09,10万元,主持;

5.第64批中国博士后面上项目,2018.07-2022.02,5万元,主持;

6.山东省博士后创新项目,2019.10-2023.06,3万元,主持;

7.青岛市博士后应用研究项目,2018.09-2022.2,5万元,主持;

8.山东大学博士后日常经费,2018.7-2022.12,2万元,主持。

代表性论文:

1.Tianyu Jiang(第一作者);Xiaoyu Bai;Minyong Li*;Advances in the Development of Bacterial Bioluminescence Imaging,Annual Review of Analytical Chemistry, 2024, Accepted.

2.Tianyu Jiang*(第一作者+并列通讯作者); Jingwen Song; Youming Zhang*; Coelenterazine-Type Bioluminescence-Induced Optical Probes for Sensing and Controlling Biological Processes,International Journal of Molecular Sciences, 2023, 24, 5074.

3. Qi Gao; Sizhe Deng;Tianyu Jiang*(通讯作者); Recent developments in the identification and biosynthesis of antitumor drugs derived from microorganisms,Engineering Microbiology, 2022, 2(4).

4. Yuexin Wu;Tianyu Jiang*(通讯作者); Developments in FRET- and BRET-Based Biosensors,Micromachines,2022 Oct 20;13(10):1789.

5.Tianyu Jiang(第一作者); Minyong Li*; Synthetic Coelenterazine Derivatives and Their Application for Bioluminescence Imaging,Methods in molecular biology, 2022 July; 2524:17-36.

6. Ancheng Ouyang; Dongmu Zhao; Xianglei Wang; Wei Zhang;Tianyu Jiang*(并列通讯作者); Aiying Li*; Wei Liu*; Covalent RGD-graphene-phthalocyanine nanocomposite for fluorescence imaging-guided dual active/passive tumor-targeted combinatorial phototherapy,Journal of Materials Chemistry B, 2022, 10(2): 3 06-320

7.Tianyu Jiang*#(第一作者+并列通讯作者); Xingye Yang#; Geng Li; Xiaohan Zhao; Tao Sun; Rolf Müller; Hailong Wang*; Minyong Li*; Youming Zhang*; Bacteria-Based Live Vehicle for In Vivo Bioluminescence Imaging,Analytical Chemistry, 2021, 93(47): 15687-15695

8. Elena V. Eremeeva#;Tianyu Jiang#(并列第一作者); Natalia P. Malikova; Minyong Li*; Eugene S. Vysotski*; Bioluminescent Properties of Semi-Synthetic Obelin and Aequorin Activated by Coelenterazine Analogues with Modifications of C-2, C-6, and C-8 Substituents,International Journal of Molecular Sciences, 2020, 21(15): 5446-5446

9.Tianyu Jiang(第一作者); Peng Zhu; Lupei Du; Minyong Li*; Identification of AI-2 Quorum Sensing Inhibitors in Vibrio harveyi Through Structure-Based Virtual Screening,Methods in molecular biology(Clifton, N.J.) 2018;1673:353-362.

10.Tianyu Jiang(第一作者); Xingye Yang; Yubin Zhou; Ilia Yampolsky; Lupei Du; Minyong Li*; New bioluminescent coelenterazine derivatives with various C-6 substitutions,Organic & Biomolecular Chemistry, 2017, 15(33): 7008-7018

11.Tianyu Jiang#(第一作者); Bowen Ke#; Hui Chen; Weishan Wang; Lupei Du; Keqian Yang; Minyong Li*; Bioluminescent Probe for Detecting Mercury(II) in Living Mice,Analytical Chemistry, 2016 Aug 2;88(15):7462-5.

12.Tianyu Jiang(第一作者); Xiaofeng Yang; Xingye Yang; Mingliang Yuan; Tianchao Zhang; Huateng Zhang; Minyong Li*; Novel bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution for Renilla luciferase,Organic & Biomolecular Chemistry,2016 Jun 21;14(23):5272-81.

13.Tianyu Jiang(第一作者); Weishan Wang; Xingkang Wu; Wenxiao Wu; Haixiu Bai; Zhao Ma; Yuemao Shen; Keqian Yang*; Minyong Li*; Discovery of New Substrates for LuxAB Bacterial Bioluminescence,Chemical Biology and Drug Design, 2016 Aug;88(2):197-208.

14.Tianyu Jiang(第一作者); Lupei Du; Minyong Li*; Lighting up bioluminescence with coelenterazine: strategies and applications,Photochemical & Photobiological Sciences,2016 Apr;15(4):466-80.

15.Tianyu Jiang(第一作者); Minyong Li*; Quorum sensing inhibitors: a patent review,Expert Opinion on Therapeutic Patents,2013 Jul;23(7):867-94.