教育背景
博士2015.09-2019.06中国科学院大学 微生物
硕士2009.11-2011.11荷兰瓦赫宁根大学 食品安全
学士2005.09–2009.06中国农业大学 食品质量与安全
工作经历
起止时间 单位名称 专业技术职务
2022. 08至今 山东大学微生物技术研究院/国家重点实验室 研究员
2021.12-2022.07中国科学院微生物研究所 副研究员
2014.10-2021.11中国科学院微生物研究所微生物资源前期开发国家重点实验室 助理研究员
2012.02-2014.09中国科学院微生物研究所微生物资源前期开发国家重点实验室 助理实验师
研究方向
1.肠道微生物培养组学
2.肠道新功能菌株发掘与机制研究
科研项目
1.2023.01-2025.12山东省泰山学者青年专家项目，75万
2.2024.01-2026.12省优青项目“肠道微生物资源收集及功能机制研究”，50万
3.2022.01-2025.12国家自然科学基金面上项目“一株产新型细菌素肠球菌的抑菌机理及潜在应用的基础研究”，58万元
4.2022.01-2026.12国家重点研发计划“变革性技术关键科学问题”专项、“高通量培养筛选鉴定健康相关微生物的关键技术”项目、“微生物高通量培养与表征”课题，105万元
5.2020.02-2024.12国家重点研发计划“合成生物学”专项、“合成生物肠道菌群体系构建及应用”项目、“重要肠道微生物的合成生物学设计与功能强化”课题，118.4万元
6.2022.12-2027.11国家重点研发计划“生物大分子与微生物组”专项、“微生物组学新技术及相关实验动物体系”项目、“菌群功能模块定向培养和理性调控技术”课题，231万元
7.2017.01-2019.12中科院重点部署项目，人体与环境健康的微生物组共性技术研究项目“非人灵长类实验动物模型肠道微生物菌株资源库的构建”课题，102万元
代表性论文
(1)Liu, Chang; Zhou, Nan; Du, Meng-Xuan; Sun, Yu-Tong; Wang, Kai; Wang, Yu-Jing; Li, Dan- Hua; Yu, Hai-Ying; Song, Yuqin; Bai, Bing-Bing; Xin, Yuhua; Wu, Linhuan; Jiang, Cheng-Ying; Feng, Jie; Xiang, Hua; Zhou, Yuguang; Ma, Juncai; Wang, Jun; Liu, Hong-Wei*; Liu, Shuang-Jiang*; The Mouse Gut Microbial Biobank expands the coverage of cultured bacteria, NATURE COMMUNICATIONS, 2020, 11(1): 79
(2) Liu, Chang#*; Du, Meng-Xuan#; Abuduaini, Rexiding#; Yu, Hai-Ying; Li, Dan-Hua; Wang, Yu-Jing; Zhou, Nan; Jiang, Min-Zhi; Niu, Peng-Xia; Han, Shan-Shan; Chen, Hong-He; Shi, Wen-Yu; Wu, Linhuan; Xin, Yu-Hua; Ma, Juncai; Zhou, Yuguang; Jiang, Cheng-Ying; Liu, Hong-Wei; Liu, Shuang- Jiang*; Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank, MICROBIOME, 2021, 9(1): 119
(3)Qiao, Shan-Shan#;Liu, Chang#; Sun, Li; Wang, Tao; Dai, Huan-Qin; Wang, Kai; Bao, Li; Li, Han-Tian; Wang, Wen-Zhao; Liu, Shuang-Jiang*; Liu, Hong-Wei*; Gut Parabacteroides merdae protects against cardiovascular damage by enhancing branched-chain amino acid catabolism, Nature Metabolism, 2022, 4(10): 1271-1286
(4)Abdugheni, Rashidin; Wang, Wen‐Zhao; Wang, Yu‐Jing; Du, Meng‐Xuan; Liu, Feng‐Lan; Zhou, Nan; Jiang, Cheng‐Ying; Wang, Chang‐Yu; Wu, Lin-Huan; Ma, Jun-Cai;Liu, Chang*; Liu, Shuang‐Jiang*; Metabolite profiling of human‐originated Lachnospiraceae at the strain level, iMeta, 2022, 1(4): e58
(5)Jiang, Yu; Du, Meng-Xuan; Xie, Li-Sheng; Jiang, Min-Zhi; Zhang, Yao-Kun; Bi, Ming-Xia;Liu, Chang*; Liu, Hong-Wei; Liu, Shuang-Jiang*; The human-derived novel gut commensal Luoshenia tenuis regulates body weight and food intake in mice, Food Science and Human Wellness, 2022
(6)Li, Dan-Hua#;Liu, Chang#; Abuduaini, Rexiding; Du, Meng-Xuan; Wang, Yu-Jing; Zhu, Hai- Zhen; Chen, Hong-He; Zhou, Nan; Xin, Yu-Hua; Wu, Lin-Huan; Ma, Jun-Cai; Zhou, Yu-Guang; Lu, Yong; Jiang, Cheng-Ying; Sun, Qiang*; Liu, Shuang-Jiang*; The monkey microbial biobank brings previously uncultivated bioresources for nonhuman primate and human gut microbiomes, mLife, 2022, 1(2): 210- 217
(7)Qiao, Shan-Shan#; Wang, Kai#;Liu, Chang#; Zhou, Nan; Bao, Li; Wang, Jun; Liu, Shuang-Jiang; Liu Hong-Wei; The enriched gut commensal Faeciroseburia intestinalis contributes to the anti- metabolic disorders effects of the Ganoderma meroterpene derivative, Food Science and Human Wellness, 2022, 11(1): 85-96
(8)Li, Dan-Hua; Abuduaini, Rexiding; Du, Meng-Xuan; Wang, Yu-Jing; Chen, Hong-He; Zhou, Nan; Zhu, Hai-Zhen; Lu, Yong; Yu, Pei-Jun; Yang, Yun-Peng; Jiang, Cheng-Ying; Sun, Qiang;Liu, Chang*; Liu, Shuang-Jiang*; Alkaliphilus flagellatus sp. nov., Butyricicoccus intestinisimiae sp. nov., Clostridium mobile sp. nov., Clostridium simiarum sp. nov., Dysosmobacter acutus sp. nov., Paenibacillus brevis sp. nov., Peptoniphilus ovalis sp. nov. and Tissierella simiarum sp. nov., isolated from monkey faeces, International Journal of Systematic and Evolutionary Microbiology, 2022, 72(3)
(9)Liu, Chang; Zhang, Bo; Liu, Yi-Ming; Yang, Ke-Qian; Liu, Shuang-Jiang*; New Intracellular Shikimic Acid Biosensor for Monitoring Shikimate Synthesis in Corynebacterium glutamicum, ACS Synthetic Biology, 2018, 7(2): 591-601
(10)Liu, Chang; Liu, Yi-Ming; Sun, Qing-Lan; Jiang, Cheng-Ying; Liu, Shuang-Jiang*; Unraveling the kinetic diversity of microbial 3-dehydroquinate dehydratases of shikimate pathway, AMB EXPRESS, 2015, 5(7): 7-7
所获专利
(1)刘双江;刘畅;杜梦璇;周楠;姜成英;一种药物候选物对于肠道菌群作用效果的体外高通量筛选平台, 2020-3-17,中国, 202010186816.3
(2)刘双江;刘畅;周楠;姜成英;杜梦璇;胆酸衍生物及其应用, 2022-2-22,中国, 202210160201.2
(3)刘双江;刘畅;杜梦璇;周楠;姜成英;一株小克里斯滕森氏菌SJ-2及其应用, 2021-5-17,中国, 2021105334244.1
(4)刘双江;刘畅;周楠;姜成英;杜梦璇;胆酸衍生物及其制备, 2022-2-22,中国, 202210160175.3
(5)刘宏伟;刘双江;刘畅;乔珊珊;代焕琴;韩俊杰;孙敬祖;粪副拟杆菌以及应用, 2021-7-12,中国, 202110786071.9
(6)刘宏伟;刘双江;乔珊珊;刘畅;罗氏菌MGB-2及其应用, 2021-2-22,中国, 202110176582.9
