代表性论文
1.XuY†, Zhao Z†, Tong WH, Ding YM, Liu B, Shi YX, Wang JC, Sun SM, Liu M, Wang YH, Qi QS, Xian M*,Zhao G*. An acid-tolerance response system protecting exponentially growingEscherichia coli.Nat Commun, 2020, 11:1496.DOI:10.1038/s41467-020-15350-5.
2.Liu M, Fu YX, Gao WJ, Xian M*,Zhao G*. Highly efficient biosynthesis of hypoxanthine inEscherichia coliand transcriptome-based analysis of the purine metabolism.ACS Synth Biol, 2020, 9(3):525-35. DOI:10.1021/acssynbio. 9b00396.
3.Zhao Z, Xian M, Liu M*,Zhao G*. Biochemical routes for uptake and conversion of xylose by microorganisms.Biotechnol Biofuels, 2020, 13:21. DOI:10.1186/s13068-020-1662-x.
4.Feng XJ, Gao WJ, Zhou YF, Zhao ZQ, Liu XT, Han XJ, Xian M*,Zhao G*. Coupled biosynthesis and esterification of 1,2,4-butanetriol to simplify its separation from fermentation broth.Eng Life Sci, 2019, 19:444-451.DOI:10.1002/elsc. 201800131.
5.Liu M, Ding YM, Xian M*,Zhao G*. Metabolic engineering of a xylose pathways for biotechnological production of glycolate inEscherichia coli.Microb Cell Fact, 2018, 17:51. DOI:10.1186/s12934-018-0900-4.
6.Feng XJ†, Jiang LQ†, Han XJ, Liu XT, Zhao ZQ, Liu HZ, Xian M*,Zhao G*. Production of D-lactate from glucose usingKlebsiella pneumoniaemutants.Microb Cell Fact, 2017, 16: 209. DOI:10.1186/s12934-017-0822-6.
7.Lactama ST， Kuiate JR, Ding YM, Xian M, Liu HZ, Boudjeko T, Feng XJ*,Zhao G*. Enhanced poly(3-hydroxypropionate) production via β-alanine pathway in recombinantEscherichia coli.PLoS One, 2017, 12:e0173150. DOI:10.1371/journal.pone.0173150.
8.Liu CS, Ding YM, Xian M, Liu M, Liu HZ, Ma QJ,Zhao G*. Malonyl-CoA pathway: a promising route for 3-hydroxypropionate biosynthesis.Crit Rev Biotechnol, 2017, 37(7):933-41. DOI:10.1080/07388551.2016. 1272093.
9.Cheng T†, Liu H†, Zou HB*, Cheng NN, Shi MX, Xie CX,Zhao G*, Xian M*. Enzymatic process optimization for thein vitroproduction of isoprene from mevalonate.Microb Cell Fact, 2017, 16:8. DOI:10.1186/s12934-016-0622-4.
10.Liu M, Ding YM, Chen HL, Zhao Z, Liu HZ, Xian M*,Zhao G*. Improving the production of acetyl-CoA-derived chemicals inEscherichia coliBL21(DE3) throughiclRandarcAdeletion.BMC Microbiol, 2017, 17:10. DOI:10.1186/s12866-016-0913-2.
11.Tong WH, Xu Y, Xian M, Niu W, Guo JT, Liu HZ*,Zhao G*. Biosynthetic pathway for acrylic acid from glycerol in recombinant Escherichia coli.Appl Mircobiol Biotechnol, 2016, 100(11): 4901-7. DOI:10.1007/s00253-015-7272-z.
12.Liu CS, Ding YM, Zhang RB, Liu HZ, Xian M*,Zhao G*. Functional balance between enzymes in malonyl-CoA pathway for 3-hydroxypropionate biosynthesis.Metab Eng, 2016, 34: 104-11. DOI:10.1016/j.ymben.2016.01.001.
13.Liu M, Yao L, Xian M, Ding YM, Liu HZ*,Zhao G*. Deletion ofarcAincreased the production of acetyl-CoA-derived chemicals in recombinantEscherichia coli.Biotechnol Lett, 2016, 38(1):97-101. DOI:10.1007/s10529-015-1953-7.
14.Feng XJ, Ding YM, Xian M, Xu X, Zhang RB,Zhao G*. Production of optically pure D-lactate from glycerol by engineeredKlebsiella pneumoniaestrain.Bioresour Technol, 2014, 172:269-75. DOI:10.1016/j.biortech. 2014.09.074.
15.Wang Q, Yang P, Xian M, Feng L, Wang JM,Zhao G*.Metabolic engineering ofEscherichia colifor poly (3-hydroxypropionate) production from glycerol and glucose.Biotechnol Lett, 2014, 36(11):2257-62. DOI:10.1007/s10529-014-1600-8.
16.Gao YQ, Liu CS, Ding YM, Sun C, Zhang RB, Xian M*,Zhao G*. Development of genetically stableEscherichia colistrains for poly(3-hydroxypropionate) production.PLoS One, 2014, 9(5): e97845. DOI:10.1371/journal.pone.0097845.
17.Wang Q, Yang P, Xian M, Liu H, Cao YJ, Yang Y,Zhao G*.Production of block copolymer poly(3-hydroxybutyrate)-block-poly(3-hydroxypropionate) with adjustable structure from inexpensive carbon source.ACS Macro Lett, 2013, 2(11): 996-1000.DOI:10.1021/mz400446g.
18.Liu CS, Wang Q, Xian M, Ding YM,Zhao G*. Dissection of malonyl-coenzyme A reductase ofChloroflexus aurantiacusresults in enzyme activity improvement.PLoS One, 2013, 8(9): e75554. DOI:10.1371/journal.pone.0075554.
19.Gao YQ†, Feng XJ†, Xian M, Wang Q,Zhao G*. Inducible cell lysis systems in microbial production of bio-based chemicals.Appl Microbiol Biotechnol, 2013, 97(16): 7121-9. DOI:10.1007/s00253-013-5100-x.
20.Wang Q, Yang P, Xian M, Yang Y, Liu CS, Xue YC,Zhao G*. Biosynthesis of Poly(3-hydroxypropionate-co-3-hydroxybutyrate) with fully controllable structures from glycerol.Bioresour Technol, 2013, 142: 741-4. DOI:10.1016/j.biortech.2013.05.121.
21.Wang Q, Yang P, Liu CS, Xue YC, Xian M*,Zhao G*. Biosynthesis of poly(3-hydroxypropionate) from glycerol by recombinantEscherichia coli.Bioresour Technol, 2013, 131: 548-51. DOI:10.1016/j.biortech.2013.01.096.
22.Wang Q, Liu CS, Xian M, Zhang YG,Zhao G*. Biosynthetic pathway for poly(3-hydroxypropionate) in recombinantEscherichia coli.J Microbiol, 2012, 50(4): 693-7. DOI:10.1007/s12275-012-2234-y.
23.Zheng YN, Li LL, Liu Q, Yang JM, Wang X, Liu W, Xu X, Liu H,Zhao G*, Xian M*. Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineeredEscherichia coli.Microb Cell Fact, 2012, 11: 65. DOI:10.1186/1475-2859-11-65.
24.Zhao G†, Kong W†, Weatherspoon N, Clark-Curtiss J, Shi Y*. Mg2+facilitates leader peptide translation to induce riboswitch-mediated transcription termination.EMBO J, 2011, 30(8): 1485-96. DOI:10.1038/emboj.2011.66. (†Contributed equally to this work)
25.Weatherspoon N†,Zhao G†, Kong W, Kong Y, Morigen, Andrews-Polymenis H, McClelland M, Shi Y*. The CpxR/CpxA two-component system upregulates two Tat-dependent peptidoglycan amidases to confer bacterial resistance to antimicrobial peptide protamine.J Biol Chem, 2011, 286(7): 5529-39. DOI:10.1074/jbc.M110.200352. (†Contributed equally to this work)
26.Zhao G, Weatherspoon N, Kong W, Curtiss R 3rd, Shi Y*. A dual-signal regulatory circuit activates transcription of a set of divergent operons inSalmonella typhimurium.P Natl Acad Sci USA,2008, 105(52): 20924-9. DOI:10.1073/pnas.0807071106.
