代表性论文:
KaiGong, Maoqin Wang, QiongDuan, Gang Li, Daojing Yong, Cailing Ren, Yue Li, Qijun Zhang, Tao Sun, Huanyun Zhang, Qiang Tu, Changsheng Wu, Jun Fu, Aiying Li, Chaoyi Song*, Youming Zhang*,Ruijuan Li*. High-yield production of FK228 and new derivatives in aBurkholderiachassis.Metab Eng2023, 75(2023): 131‒142.
Wentao Zheng#, Yandong Xia#, Xue Wang, Shiqing Gao, Diao Zhou, Vinothkannan Ravichandran, Chanjuan Jiang, Qiang Tu, Yulong Yin, Youming Zhang, Jun Fu*,Ruijuan Li*, Jia Yin*.Precise genome engineering inPseudomonasusing phage-encoded homologous recombination and Cascade-Cas3 system.Nat Protoc2023, 18(9): 2642-2670.
Yuxin Cao#, Linfeng Wang#, Cailing Ren#, Chenxi Li, Yang Liu, Tong Zhang, Mengjiao Luo, Pan Zhao,Ruijuan Li*, Jun Fu*, Jia Yin*. Oral supplementation of Pediococcus pentosaceus ameliorates hyperuricemia and alcohol-induced injury.Appl Environ Microbiol.2026, 92(4):e0024626.
Xiuling Wang, Ping Lin, Qiyao Shen, Xueyan Feng,Shouying Xu,Qijun Zhang, Yang Liu, Cailing Ren, Daojing Yong, Qiong Duan,Liujie Huo,Youming Zhang, Gang Li*, Jun Fu*,Ruijuan Li*. A highly efficient heterologous expression platform to facilitate the production of microbial natural products inStreptomyces.Microb Cell Fact2025,24(1):105.
Shiqing Gao#,Xiuling Wang#,Runyu Yang, Zhilong Bian, Daojing Yong, Shouying Xu, Liujie Huo, Qiang Tu, Youming Zhang, Jun Fu*, andRuijuan Li*. Efficient genome engineering inAgrobacterium tumefaciensC58 using recombineering assisted by CRISPR/Cas9.J Biotechnol.2025,406: 99-104.
Xiuling Wang#,Shiqing Gao#,Jun Fu*,Ruijuan Li*.Heterologous expression of the nitrogen-fixing gene cluster fromPaenibacillus polymyxainBacillus subtilis.Microorganisms2025, 13(6), 1320.
Daojing Yong, Yingying Yu, Shuai Zhao, Shoudong Cui, Shuai Zhu, Zonglin Yang,Yue Li, Qijun Zhang, Shiqing Gao, Junchi Ma, Aiying Li, Jun Fu, Jinfeng Ni*, Youming Zhang* andRuijuan Li*.Mechanisms of biocontrol of gray moldinpostharvest pear fruitsusing thetermite symbiontStreptomyces griseusH3950.Plant Physiol Bioch2025,224:109892.
Xiuling Wang,Zhuo Zhang, Jun Fu*,Ruijuan Li*.Genomics-driven discovery ofplantariitinA, a novel lipopeptide inBurkholderia plantariiDSM9509.Molecules2025, 30(4):868.
Runyu Yang, Yitong Shi, Jinyu Bian, Mengxiao Sun, Junchi Ma, Cailing Ren, Xueyan Feng, Yun Wang, Yuanhui Yang, Jianqiang Zhou*, Jun Fu*, andRuijuan Li*. Genetically engineeredPseudomonas aeruginosawith lipase regulation for production of rhamnolipids from waste frying oil.Front Microbiol2025, 16:1691217.
Qingshu Liu#,Ruijuan Li#,*, Hongbo Shi, Runyu Yang, QiyaoShen, Qingwen Cui, Xiuling Wang, Aiying Li, Youming Zhang*, Jun Fu*. A recombineering system in Bacillus subtilis based on the native phage recombinase pair YqaJ/YqaK.Engineering Microbiology2023, 3(3): 100099.
Ruijuan Li, Aiying Li, Youming Zhang, Jun Fu*. The emerging role of recombineering in microbiology.Engineering Microbiology2023, 3(3): 100097.
Zhilong Bian, Shanshan Li, Runyu Yang, Jia Yin, Youming Zhang, Qiang Tu*, Jun Fu*,Ruijuan Li*. Development of a new recombineering system forAgrobacteriumspecies.Appl Environ Microbiol.2022, 88(5): e0249921.
Daojing Yong, Yue Li, Kai Gong, Yingying Yu, Shuai Zhao, Qiong Duan, Cailing Ren, Aiying Li, Jun Fu, Jinfeng Ni*, Youming Zhang*andRuijuan Li*. Biocontrol of strawberry gray mold caused byBotrytis cinereawith the termite associatedStreptomycessp. sdu1201 and actinomycin D.Front Microbiol.2022, 13:1051730.
Khorshed Alam, Yiming Zhao, Kai Gong, Lin Zhong, Md. Mahmudul Islam, Saiful Islam, Geng Li,Ruijuan Li*, Youming Zhang*, Aiying Li*. Isolation, complete genome sequencing and in silico genome mining ofBurkholderiafor secondary metabolites.BMC Microbiol2022, 22:323.
Khorshed Alam#, Jinfang Hao#, Lin Zhong, Guoqing Fan, Qing Ouyang, Md. Mahmudul Islam, Saiful Islam, Hongluan Sun, Youming Zhang,Ruijuan Li*, Aiying Li*. Complete genome sequencing and in silico genome mining reveal the promising metabolic potential inStreptomycesstrain CS-7.Front Microbiol.2022, 13:939919.
Wentao Zheng#, Yandong Xia#, Xue Wang, Shiqing Gao, Diao Zhou, Jun Fu*,Ruijuan Li*, Jia Yin*. Cascade-Cas3 facilitates high-accuracy genome engineering inPseudomonasusing phage-encoded homologous recombination.Engineering Microbiology2022, 2(4): 100046.
Kai Gong#, Daojing Yong#, Jun Fu, Aiying Li, Youming Zhang,Ruijuan Li*.Diterpenoids fromStreptomyces: Structures, Biosyntheses and Bioactivities.ChemBioChem.2022, 23(17): e202200231.
Xiaotong Wang, Chaoyi Song, Qingsheng Qi, Youming Zhang*,Ruijuan Li*, Liujie Huo*. Biochemical characterization of a polyethylene terephthalate hydrolase and design of a high-throughput screening for its directed evolution.Engineering Microbiology2022, 2(2), 100020.
Ruijuan Li#, Hongbo Shi#, Xiaoyu Zhao, Xianqi Liu, Qiong Duan, Chaoyi Song, Hanna Chen, Wentao Zheng, Qiyao Shen, Maoqin Wang, Xue Wang, Kai Gong, Jia Yin, Youming Zhang*, Aiying Li*, Jun Fu*. Development and application of an efficient recombineering system forBurkholderia glumaeandBurkholderia plantarii.Microb Biotechnol2021, 14(4): 1809‒1826.
Khorshed Alam, Md. Mahmudul Islam, Caiyun Li, Sharmin Sultana, Lin Zhong, Qiyao Shen, Guangle Yu, Jinfang Hao, Youming Zhang,Ruijuan Li*, Aiying Li*. Genomemining ofPseudomonasspecies: diversity and evolution of metabolic and biosynthetic potential.Molecules.2021, 26, 7524.
Khorshed Alam, Md. Mahmudul Islam, Kai Gong, Muhammad Nazeer Abbasi,Ruijuan Li*, Youming Zhang*, Aiying Li*. In silicogenome mining of potential novel biosynthetic gene clusters for drug discovery fromBurkholderiabacteria.Comput Biol Med.2021, 140 (2022) 105046.
Caiyun Li, Khorshed Alam, Yiming Zhao, Jinfang Hao, Qing Yang, Youming Zhang*,Ruijuan Li*, Aiying Li*. Mining and biosynthesis of bioactive lanthipeptides from microorganisms.Front Bioeng Biotech2021, 9(639): 692466.
Ruijuan Li#, Linda Helbig#, Jun Fu, Xiaoying Bian, Jennifer Herrmann, Michael Baumann, A. Francis Stewart, Rolf Müller, Aiying Li*, Daniel Zips*, and Youming Zhang*. Expressingcytotoxiccompounds inEscherichia coliNissle 1917 fortumor-targetingtherapy.Res Microbiol2019, 170(2): 74–79.
Ruijuan Li#, Song Wang#, Gang Li, Jinchuan Zhou, Jiaozhen Zhang, Youming Zhang, Guosheng Shi, and Hongxiang Lou*.Four new kaurane diterpenoidsfrom the Chinese liverwortJungermannia comataNees.Chem Biodivers2016, 13(12): 1685–1690.
Ruijuan Li, Yu Zhao, Harukuni Tokuda, Xiaoming Yang, Yuehu Wang, Qian Shi, Susan L. Morris-Natschke, Hongxiang Lou*, and Kuo-Hsiung Lee*. Total synthesis of plagiochin G and its derivatives as potential cancer chemopreventive agents.Tetrahedron Lett2014, 55(2014): 6500−6503.
Song Wang,#Ruijuan Li,#Rongxiu Zhu, Jinchuan Zhou, Zhaomin Lin, Jiaozhen Zhang, Jingyi Wu, Yaqi Kang, Susan L. Morris-Natschke, Kuo-Hsiung. Lee, and Hongxiang Lou*. Notolutesins A−J, dolabrane-type diterpenoids from the Chinese liverwortNotoscyphus lutescens.J Nat Prod2014, 77(9): 2081−2087.
Ruijuan Li, Rongxiu Zhu, Yu Zhao, Susan L. Morris-Natschke, Chin-Ho Chen, Song Wang, Jiaozhen Zhang, Jinchuan Zhou, Hongxiang Lou*, and Kuo-Hsiung Lee*. Two new cadinane-type sesquiterpenes from the Chinese liverwortFrullania serrata.Nat Prod Res2014, 28: 1519−1524.
Ruijuan Li, Yi Sun, Bin Sun, Xiaoning Wang, Shanshan Liu, Jinchuan Zhou, Jianping Ye, Yu Zhao, Lei Liu, Kuo-Hsiung Lee, and Hongxiang Lou*. Phytotoxiccis-clerodane diterpenoids from the Chinese liverwortScapania stephanii.Phytochemistry2014, 105(2014): 85−91.
Ruijuan Li,#Zhaomin Lin,#Yaqi Kang, Yanxia Guo, Xin Lv, Jinchuan Zhou, Song Wang, and Hongxiang Lou*. Cembrane-type diterpenoids from the Chinese liverwortsChandonanthus hirtellusandC. birmensis.J Nat Prod2014, 77(2): 339−345.
Ruijuan Li, Rongxiu Zhu, Yaoyao Li, Jinchuan Zhou, Jiaozhen Zhang, Song Wang, Jianping Ye, Yuehu Wang, Susan L. Morris-Natschke, Kuo-Hsiung Lee, and Hong-Xiang Lou*.Secondary metabolites from the Chinese liverwortCephaloziella kiaeri.J Nat Prod2013,76(9): 1700−1708.
Ruijuan Li, Dongxiao Guo, and Hongxiang Lou*. A new guaiane-type sesquiterpene lactone from the Chinese liverwortPorella acutifoliasubsp.tosana.Chin J Nat Med2013,11(1): 0074−0076.
