科研项目:
主持多项国家级、省部级项目，累计获批经费超过300万元。
1.2024-2027，在体智能进化技术及应用，国家重点研发计划（2024YFC3407100），子课题负责人
2.2024-2027，具有工业应用价值高效PET解聚酶的定向进化，山东省自然基金面上项目（ZR2024MC070），主持
3.2023-2025，定向进化低pH适应性的高效PET解聚酶，国家自然科学基金青年项目（32200081），主持
4.2022-2027，神经酰胺与血红素的发酵数据数字化，国家重点研发计划（2022YFC3401301），子课题负责人
5.2021-2024，微生物基因组的设计与切分，国家重点研发计划（2021YFC2100501），子课题负责人
6.2022-2024，建立基于CRISPRi/a的多基因组合表达调控平台高效生物合成N-乙酰神经氨酸，山东省自然科学基金青年项目（ZR2021QC021），主持
7.2019-2020，基于非同源末端连接的大肠杆菌基因组高通量删减，中国博士后科学基金面上项目(2019M662341)，主持
8.2019-2020，大肠杆菌多基因组合表达调控技术的开发及其应用，青岛市博士后应用研究项目，主持
9.2023-2025，Bioplastics upcyclig loop (BioPolyCycle)，ANSO Collaborative Research in 2022，参与
10.2020-2023，塑料解聚及资源化微生物菌群的人工构建，国家自然科学基金国际(地区)合作与交流项目（31961133014），参与
11.2018-2022，利用非同源末端连接的基因组精简策略构建最适细胞工厂，国家自然科学基金重点项目（31730003），参与
代表性论文:
1.Zheng Y#, Li Q#, Liu P, Yuan Y, Dian L, Wang Q, Liang Q,Su T*, Qi Q*. 2024. Dynamic Docking-Assisted Engineering of Hydrolases for Efficient PET Depolymerization,ACS Catal.
2.Su T, Pang Q, Qi Q. 2024. In Vivo DNA Assembly Using the PEDA Method,Methods in molecular biology.
3.Liu P, Zheng Y, Yuan Y, Han Y,Su T*, Qi Q*. 2023. Upcycling of PET oligomers from chemical recycling processes to PHA by microbial co-cultivation,Waste Manage.
4.Yuan Y, Liu P, Zheng Y, Li Q, Bian J, Liang Q,Su T*, Dian L*, Qi Q. 2023.Unique Raoultella species isolated from petroleum contaminated soil degrades polystyrene and polyethylene,Ecotox Environ Safe.
5.Su T#, Zhang T#, Liu P, Bian J, Zheng Y, Yuan Y, Li Q, Liang Q, Qi Q*.2023. Biodegradation of polyurethane by the microbial consortia enriched from landfill.Appl Microbiol Biotechnol.
6.Liu P, Zheng Y, Yuan Y, Zhang T, Li Q, Liang Q,Su T*, Qi Q*.2022. Valorization of Polyethylene Terephthalate to Muconic Acid by EngineeringPseudomonas Putida.Int J Mol Sci.
7.Pang Q, Ma S, Han H, Jin X, Liu X,Su T*, Qi Q*.2022. Phage Enzyme-Assisted DirectIn VivoDNA Assembly in Multiple Microorganisms.ACS Synth Biol.
8.Chang Y, Wang Q,Su T*, Qi Q*.2021. Identification of phage recombinase function unit in genusCorynebacterium.Appl Microbiol Biotechnol.
9.Su T, Guo Q, Zheng Y, Chang Y, Gu F, Lu X, Qi Q*.2021. Base editing-coupled survival screening enabled high-sensitive analysis of PAM compatibility and finding of the new possible off-target.iScience.
10.Su T, Guo Q, Zheng Y, Liang Q, Wang Q*, Qi Q*.2019. Fine-Tuning ofhemBUsing CRISPRi for Increasing 5-Aminolevulinic Acid Production inEscherichia coli.Front Microbiol.
11.Su T#,Liu F#, Chang Y, Guo Q, Wang J, Wang Q, Liang Q, Qi Q*.2019.The phage T4 DNA ligase mediates bacterial chromosome DSBs repair as single component non-homologous end joining.Synth Syst Biotechnol.
12.Su T, Jin H, Zheng Y, Zhao Q, Chang Y, Wang Q, Qi Q*.2018.Improved ssDNA recombineering for rapid and efficient pathway engineering inCorynebacterium glutamicum.J Chem Technol Biotechnol.
13.Su T, Liu F, Gu P, Jin H, Chang Y, Wang Q, Liang Q, Qi Q*.2016.A CRISPR-Cas9 Assisted Non-Homologous End-Joining strategy for one-step engineering of bacterial genome.Sci Rep.
14.Li Q, Zheng Y,Su T, Wang Q, Liang Q, Zhang Z, Qi Q*, Tian J*.2022. Computational design of a cutinase for plastic biodegradation by mining molecular dynamics simulations trajectories.Comput Struct Biotec.
人才称号
2023，山东省泰山学者青年专家
学术兼职
Frontiers in Microbiology, Review Editor
所获专利
1. 一种利用T4脱氧核糖核酸连接酶提高原核微生物诱变育种效率的方法，CN109321585A
2. 一种噬菌体酶辅助的体内DNA片段组装方法、试剂盒及其应用，CN114438073A
