研究方向
1.微生物资源与利用
2.微生物-植物相互作用
3.真菌次级代谢产物的生物合成及其生物学功能研究
科研项目
国家重点研发计划项目子课题，极地微生物酶的挖掘、应用潜力评价与制备技术，2022YFC2807503-3，2022.12-2026.11，主持
国家自然科学基金面上项目，木霉驱动的根际微生物群落变化及其生态机制的宏组学研究，31971535，2020. 1 -2023.12，主持
国家重点研发计划项目子课题，基于造礁珊瑚与微生物互作的岛礁生境修复技术与示范，2018YFC1406504-3，2018.08 -2021.12，主持
山东省重点研发计划，生姜专用药肥双效木霉菌剂及其应用技术的研究，2017GSF21106，2017.1-2018.12，主持
国家自然科学基金面上项目，木霉次级代谢产物Trichokonins生物合成基因簇的鉴定及Lae1因子对其生物合成的调控作用，31570042，2016.1-2019.12，主持
国家自然科学基金面上项目，木霉产生的Trichokonins促进植物根系生长的作用与机制，31270064，2013.1-2016.12，主持
863计划子课题，木霉多肽植物免疫调节剂的中试研究，2011AA09070403，2011.7-2014.7，主持
代表性论文
Yu-Qiang Zhang#, Shan Zhang#, Mei-Ling Sun, Hai-Nan Su, Hao-Yang Li, Kun-Liu, Yu-Zhong Zhang, Xiu-Lan Chen, Hai-Yan Cao*, Xiao-Yan Song*. Antibacterial activity of peptaibols fromTrichoderma longibrachiatumSMF2 against gram-negativeXanthomonas oryzaepv.oryzae, the causal agent of bacterial leaf blight on rice. Frontiers in Microbiology. 2022. 13:1034779.
Xiao-yan He, Na Li, Xiu-lan Chen, Yu-zhong Zhang, Xi-ying Zhang *, Xiao-yan Song*.Pedobacter indicussp.nov., isolated from deep-sea sediment. Antonie van Leeuwenhoek. 2020, 113: 357–364.
Mei-Ling Sun, Fang Zhao, Xing-Kun Zhang, Xi-Ying Zhang, Yu-Zhong Zhang, Xiao-Yan Song* & Xiu-Lan Chen*. Improvement of the production of an Arctic bacterial exopolysaccharide with protective effect on human skin cells against UV-induced oxidative stress. Appl Microbiol Biotechnol, 2020,104(11): 4863-4875.
Jin-Chao Shi#, Wei-Ling Shi#, Yan-Rong Zhou#, Xiu-Lan Chen, Yu-Zhong Zhang, Xia Zhang*, Wei-Xin Zhang* and Xiao-Yan Song*. The putative methyltransferase TlLAE1 is involved in the regulation of peptaibols production in the biocontrol fungusTrichoderma longibrachiatumSMF2. Front. Microbiol., 2020, 11:1267.
Xiao-Han Guo#, Ning Wang, Xiao-Xue Yuan, Xi-Ying Zhang, Xiu-Lan Chen, Yu-Zhong Zhang, Xiao-Yan Song*.Poseidonibacter antarcticussp.nov., isolated from Antarctic intertidal sediment. Int J Syst Evol Microbiol. 2019, 69(9):2717-2722.
Jin-Cheng Rong, Qian-Qian Cha, Xue-Bing Ren, Bin-Bin Xie, Xiao-Yan Song*, Complete genome sequence ofPseudoalteromonas espejianaDSM9414T, an amino-acid-requiring strain from seawater. Mar Genomics. 2018, 38:21-23.
Xiu-Lan Chen#, Ming Peng#, Jing Li#, Bai-Lu Tang, Xuan Shao, Fang Zhao, Chang Liu, Xi-Ying Zhang, Ping-Yi Li, Mei Shi, Yu-Zhong Zhang, Xiao-Yan Song*, Preparation and functional evaluation of collagen oligopeptide-rich hydrolysate from fish skin with the serine collagenolytic protease fromPseudoalteromonassp. SM9913. Sci Rep., 2017, 7(1): 15716
Wei-Ling Shi, Xiu-Lan Chen, Li-Xia Wang, Zhi-Ting Gong, Shuyu Li, Chun-Long Li, Bin-Bin Xie, Wei Zhang, Mei Shi, Chuanyou Li, Yu-Zhong Zhang and Xiao-Yan Song*. Cellular and molecular insight into the inhibition of primary root growth ofArabidopsisinduced by peptaibols, a class of linear peptide antibiotics mainly produced byTrichodermaspp. J Exp Bot., 2016，67: 2191-2205.
Fei Xu, Xi-Ying Zhang, Chang Liu, Mei Shi, Hai-Nan Su, Qi-Long Qin, Chen Xiu-Lan, Zhang Yu-Zhong, Song Xiao-Yan*.Subsaxibacter arcticussp.nov., isolated from Arctic intertidal sand. Int J Syst Evol Microbiol. 2016, 66(1):132-136.
Bin-Bin Xie, Dan Li, Wei-Ling Shi, Qi-Long Qin, Xiao-Wei Wang, Jin-Cheng Rong, Cai-Yun Sun, Feng Huang, Xi-Ying Zhang, Xiao-Wei Dong, Xiu-Lan Chen, Bai-Cheng Zhou, Yu-Zhong Zhang, Xiao-Yan Song*. Deep RNA sequencing reveals a high frequency of alternative splicing events in the fungus.Trichoderma longibrachiatum.BMC Genomics. 2015 Feb; 16(1): 54.
Bin-Bin Xie, Qi-Long Qin, Mei Shi, Lei-Lei Chen, Yan-Li Shu, Yan Luo, Xiao-Wei Wang, Jin-Cheng Rong, Zhi-Ting Gong, Dan Li, Cai-Yun Sun, Gui-Ming Liu, Xiao-Wei Dong, Xiu-Hua Pang, Feng Huang, Wei feng Liu, Xiu-Lan Chen, Bai-Cheng Zhou, Yu-Zhong Zhang*, Xiao-Yan Song*. Comparative Genomics Provide Insights into Evolution ofTrichodermaNutrition Style. Genome Biol Evol. 2014 Feb; 6(2): 379–390.
Hai-Yun Li, Yan Luo, Xiu-Sheng Zhang, Wei-Ling Shi, Zhi-Ting Gong, Mei Shi, Lei-Lei Chen, Xiu-Lan Chen, Yu-Zhong Zhang, Xiao-Yan Song*. Trichokonins from Trichoderma pseudokoningii SMF2 induce resistance against Gram-negativePectobacterium carotovorumsubsp.carotovorumin Chinese cabbage. FEMS Microbiol Lett. 2014 May;354(1):75-82.
