主持项目
先后主持包括6项国家自然科学基金,2项国家863计划、国家973计划、国际合作项目、多项省级重大重点项目等在内的各类项目20多项,以及与中粮集团、中国石油等多家企业合作的多个横向课题。近年来部分课题如下:
国家自然科学基金面上项目:纤维素酶在木质素上的吸附规律和机制及弱木质素吸附性酶的构建, 2019-2022
山东省重点研发计划(重大科技创新工程)项目:杜仲木质纤维素高值化利用关键技术,2019-2021
中石油合作横向课题:高效纤维素酶菌株构建及发酵产酶技术研究,2018-2023
山东省自然科学基金(重大基础类):木质纤维素类生物质高效降解转化的关键机理研究,2019-2024
山东省重点研发计划:甜高粱秆固体发酵残渣生物转化生产液体燃料乙醇及其综合利用研究,2019-2021
国家自然科学基金面上项目:木质纤维素材料预处理过程中木质素结构和性质的变化及其对纤维素酶吸附的影响及机制,2013-2016
山东省自主创新重大专项:造纸行业生物质主流组分分离与高值利用关键技术研究与示范,2014-2017
国家973计划(2011CB707401):生物质预处理及对纤维素酶解与转化的影响机制,2011-2015
国家863计划(2012AA022203B):造纸用木质素酶和纤维素酶的分子改造及应用,2012-2015
研究成果
以第一或通讯作者在国内外发表研究论文100多篇,其中SCI、EI等收录80多篇;已授权国家发明专利11件;参与编写著作3部,译著1部。
近年来发表的部分文章:
1 Tiantian Yang, Yingjie Guo, Na Gao, Xuezhi Li, Jian Zhao*.Modification of a cellulase system by engineering Penicillium oxalicum to produce cellulose nanocrystal,Carbohydrate Polymers, 2020, Vol 234, 115862 IF 7.182 (一区)
2 Tiantian Yang, Xuezhi Li, Yingjie Guo, Shengjuan Peng, Guodong Liu, Jian Zhao*.Effect of endoglucanases from different glycoside hydrolase families on enzymatic preparation of cellulose nanocrystal. Industrial Crops and Products,155(2020): 112755 IF4.244(一区)
3 Daolei Zhang, Xuezhi Li*, Jian Zhao*.Fusarium concolor X4 pretreatment suppresses light-induced yellowing of high-yield pulp.BioMed Research International, Volume 2020, Article ID 9497215
4 Fenfen Guo,Xuezhi Li*, Jian Zhao*, Guanxi Li, Peike Gao, Xiaolong Han. Optimizing Culture Conditions by Statistical Approach to Enhance Production of Pectinase fromBacillus sp. Y1. BioMed Research International. Volume 2019, Article ID 8146948
5 Yanan Li; Yueyan Hu; Zhu Zhu; Kaili Zhao; Guodong Liu; Lushan Wang; Yinbo Qu; Jian Zhao; Yuqi Qin*. Normal transcription of cellulolytic enzyme genes relies on the balance between the methylation of H3K36 and H3K4 inPenicillium oxalicum.Biotechnology for Biofuels, 2019, 12:198 (JCR一区),IF 6.343
6Ya'nan Li, Yueyan Hu, Kaili Zhao, Yunjun Pan, Yinbo Qu, Jian Zhao, Yuqi Qin*. The indispensable role of histone methyltransferase PoDot1 in extracellular glycoside hydrolase biosynthesis ofPenicillium oxalicum, Frontiers in Microbiology, 2019, 10: 2566(JCR一区) IF 4.840
7 Xianqin Lu, Xiaoting Feng, Xuezhi Li, Jian Zhao*. Binding and hydrolysis properties of engineered cellobiohydrolases and endoglucanases. Bioresource Technology, 2018. 267:235-241(一区)IF6.669
8 Xianqin Lu, Xiaoting Feng, Xuezhi Li, Jian Zhao*. The adsorption properties of endoglucanase to lignin and their impact on hydrolysis, Bioresource Technology, 2018. 267:110-116(一区)IF6.669
9 Can Wang, Xianqin Lu, Jia Gao, Xuezhi Li, Jian Zhao*. Xylo-oligosaccharides Inhibit Enzymatic Hydrolysis by Influencing Enzymatic Activity of Cellulase from Penicillium oxalicum, Energy & Fuels, 2018, 32:9427-9437 (二区)
10 Jian Du, Wenxia Song, Xiu Zhang, Jian Zhao, Guodong Liu, Yinbo Qu*, Differential Reinforcement of enzymatic hydrolysis by adding chemicals and accessory proteins to high solid loading substrates with different pretreatments. Bioprocess and Biosystems Engineering 2018, 41:1153-1163
11 Jian Du, Yuan Cao, Guodong Liu, Jian Zhao, Xuezhi Li, Yinbo Qu*. Identifying and overcoming the effect of mass transfer limitation on decreased yield in enzymatic hydrolysis of lignocellulose at high solid concentrations. Bioresource Technology, 2017,229:88-95(一区)IF5.807
12 Meimei Wang,·Yanxin Ye,·Xuezhi Li,·Hao Chen,·Jian Zhao*, Utility of co-expressed alkali-tolerant endoglucanase and xylanase in ameliorating wheat straw chemical pulp properties, Cellulose, 2017, 24(5), 2299-2311 (一区)
13Yanxin Ye, Xuezhi Li, Yuan Cao, Jian Du, Shicheng Chen, Jian Zhao*.A β-xylosidase hyper-production Penicillium oxalicum mutant enhanced ethanol production from alkali-pretreated corn stover. Bioresource Technology, 2017,245:734-742 (一区)IF5.807
14Yanxin Ye, Xuezhi Li, Jian Zhao*.Production and Characteristics of a Novel Xylose- and Alkali-tolerant GH 43 β-xylosidase fromPenicillium oxalicum for Promoting Hemicellulose Degradation. Scientific Reports, 2017, 7:11600 (二区)
15 Xianqin Lu, Can Wang, Xuezhi Li, Jian Zhao*. Temperature and pH influence adsorption of cellobiohydrolase onto lignin by changing the protein properties. Bioresource Technology, 2017,245:819-825 (一区) IF5.807
16 Meimei Wang, Jian Du, Daolei Zhang, Xuezhi Li, Jian Zhao*.Modification of Different Pulps by Homologous Overexpression Alkali-Tolerant Endoglucanase inBacillus subtilis Y106, Scientific Reports, 2017, 7:3321(二区)
17 Xianqin Lu, Can Wang, Xuezhi Li, Jian Zhao*, Xuebing Zhao.Studying nonproductive adsorption ability and binding approach of cellobiohydrolase to lignin during bioconversion of lignocellulose, Energy & Fuels, 2017,31 (12): 14393–14400,2017-10-19(二区)
18Liping Tan, Meimei Wang, Xuezhi Li, Hongxing Li,Jian Zhao*,Yinbo Qu, Yuen May Choo, Soh Kheang Loh. Fractionation of oil palm empty fruit bunch by bisulfite pretreatment for the production of bioethanol and high value products, Bioresource Technology, 2016, 200: 572-578 (一区) IF 5.651
19 Xianqin Lu,XiaojuZheng,Xuezhi Li, Jian Zhao*.Adsorption and mechanism of cellulase enzymes onto lignin isolated from corn stover pretreated with liquid hot water, Biotechnology for Biofuels, 2016, 9:118-129 (JCR一区),IF7.398 (5-years)
20 Daolei Zhang, Xuezhi Li*, Meimei Wang, Yanxin Ye, Jian Du, Xianqin Lu, Jian Zhao*. Xylanase Treatment Suppresses Light- and Heat-Induced Yellowing of Pulp, Scientific Reports, 2016,6:38374,(二区),IF5.525(5-years)
21 Yanan Li, Xiaoju Zheng, Xiujun Zhang, Longfei Bao, Yingying Zhu, Yinbo Qu, Jian Zhao*, Yuqi Qin*. The Different Roles of Penicillium oxalicum LaeA in the Production of Extracellular Cellulase andβ-xylosidase, Frontiers in Microbiology, 2016,7: 2091 (JCR一区),IF 4.165